LncRNA-CIR promotes articular cartilage degeneration in osteoarthritis by regulating autophagy

• Published in: Biochemical and biophysical research communications Vol. 505; no. 3; pp. 692 - 698
• Main Authors: Wang, Cheng-Long, Peng, Jian-Ping, Chen, Xiao-Dong
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 02.11.2018
• Subjects: 60 APPLIED LIFE SCIENCES; Autophagy; CARTILAGE; Cartilage degeneration; extracellular matrix; histopathology; immunohistochemistry; INFLAMMATION; lncRNA-CIR; non-coding RNA; Osteoarthritis; patients; PROTEINS; RNA; lncRNA-CIR; Cartilage degeneration; Autophagy; Osteoarthritis

Osteoarthritis (OA) is a common joint disease that is regarded as a local inflammatory response caused by joint instability and accompanied by the progressive degeneration of articular cartilage. However, the molecular mechanisms involved in the maintenance of articular cartilage remain a subject of...