Dental pulp stem cells promote genioglossus repair and systemic amelioration in chronic intermittent hypoxia

• Published in: iScience Vol. 27; no. 11; p. 111143
• Main Authors: Zhang, Meng-Han, Zhang, Wei-Hua, Lu, Yun, Yu, Li-Ming, Han, Xin-Xin, Xu, Yan, Wu, Meng-Jie, Ding, Wang-Hui, Liu, Yue-Hua
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.11.2024; Elsevier
• Subjects: Cell biology; Molecular biology; Stem cells research; Cell biology; Molecular biology; Stem cells research

Obstructive sleep apnea (OSA) leads to chronic intermittent hypoxia (CIH) and is not well addressed by current therapies. The genioglossus (GG) is the largest upper airway dilator controlling OSA pathology, making its repair a potential treatment. This study investigates dental pulp stem cells (DPSC...