Molecular classification of hepatocellular carcinoma: potential therapeutic implications

• Published in: Hepatic oncology Vol. 2; no. 4; pp. 371 - 379
• Main Authors: Goossens, Nicolas, Sun, Xiaochen, Hoshida, Yujin
• Format: Journal Article
• Language: English
• Published: England Future Medicine Ltd 01.10.2015
• Subjects: clinical trial; hepatocellular carcinoma; molecular classification; molecular targeted therapy; Review; clinical trial; molecular targeted therapy; hepatocellular carcinoma; molecular classification

Genomic profiling of hepatocellular carcinoma (HCC) tumors has elucidated recurrent molecular aberrations common or specific to disease etiology, patient race or geographic regions, allowing the classification of HCC tumors into subclasses sharing similar molecular and clinical characteristics. Prev...