Interferon Gamma Release Assays for Diagnosis of Pleural Tuberculosis: a Systematic Review and Meta-Analysis

• Published in: Journal of clinical microbiology Vol. 53; no. 8; pp. 2451 - 2459
• Main Authors: Aggarwal, Ashutosh N., Agarwal, Ritesh, Gupta, Dheeraj, Dhooria, Sahajal, Behera, Digambar
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.08.2015
• Subjects: Antigens, Bacterial - analysis; Blood - microbiology; Diagnostic Tests, Routine - methods; Humans; Immunoassays; Interferon-gamma Release Tests - methods; Mycobacterium; Pleural Effusion - microbiology; ROC Curve; Sensitivity and Specificity; Tuberculosis, Pleural - diagnosis

The role of interferon gamma release assays (IGRAs), although established for identifying latent tuberculosis, is still evolving in the diagnosis of active extrapulmonary tuberculosis. We systematically evaluated the diagnostic performance of blood- and pleural fluid-based IGRAs in tuberculous pleur...