Human melanoma-associated antigens: analysis of antigenic heterogeneity by molecular, serologic and flow-cytometric approaches

• Published in: Molecular immunology Vol. 23; no. 2; p. 193
• Main Authors: Morgan, Jr, A C, Woodhouse, C, Bartholemew, R, Schroff, R
• Format: Journal Article
• Language: English
• Published: England 01.02.1986
• Subjects: Antibodies, Monoclonal - immunology; Antigens, Neoplasm - immunology; Electrophoresis, Polyacrylamide Gel; Epitopes - analysis; Flow Cytometry; Humans; Immunoenzyme Techniques; Melanoma - immunology; Skin Neoplasms - immunology

The relationship of antigenic heterogeneity to the epitope recognized by an antibody was examined with monoclonal antibodies to human melanoma-associated antigens. Expression of the human melanoma-associated antigens, 250-Kd glycoprotein/proteoglycan and p97, was examined quantitatively by flow cyto...