Switching between parathormone (PTH) assays: the impact on the diagnosis of renal osteodystrophy

• Published in: Clinical chemistry and laboratory medicine Vol. 51; no. 6; pp. 1251 - 1256
• Main Authors: Bekő, Gabriella, Butz, Henriett, Berta, Klára, Tislér, András, Olajos, Ferenc, Vásárhelyi, Barna, Patócs, Attila
• Format: Journal Article
• Language: English
• Published: Germany De Gruyter 01.06.2013; Walter De Gruyter & Company
• Subjects: Adult; Aged; Aged, 80 and over; Assaying; Biomedical materials; chronic kidney disease; Chronic Kidney Disease-Mineral and Bone Disorder - blood; Chronic Kidney Disease-Mineral and Bone Disorder - diagnosis; Classification; Decision making; Dialysis; Female; Guidelines; Hemodialysis; Humans; Hyperparathyroidism; intact PTH; Kidney diseases; Kidney Failure, Chronic - blood; Kidney Failure, Chronic - diagnosis; Male; Mathematical analysis; Middle Aged; Osteodystrophy; parathormone (PTH) measurement; Parathyroid hormone; Parathyroid Hormone - blood; Patients; Practice Guidelines as Topic; PTH(1-84); Renal osteodystrophy; secondary hyperparathyroidism; Switching; Young Adult

Clinical guidelines for decision-making in chronic kidney disease (CKD) consider parathormone (PTH) levels. The measured PTH values differ if novel full length PTH(1-84) assays are used instead of earlier intact iPTH assays. In this study we analyzed how the classification of CKD patients alters whe...