Flow cytometric quantitation of T cell phenotypes in cerebrospinal fluid and peripheral blood of homosexual men with and without antibodies to human immunodeficiency virus, type I

• Published in: Journal of neuroimmunology Vol. 20; no. 1; pp. 73 - 81
• Main Authors: Margolick, Joseph B., McArthur, Justin C., Scott, Elvia R., McArthur, Julie H., Cohn, Sylvia, Farzadegan, Homayoon, Frank Polk, B.
• Format: Journal Article
• Language: English
• Published: London Elsevier B.V 01.11.1988; Amsterdam Elsevier; New York, NY
• Subjects: Adult; Antigens, Differentiation, T-Lymphocyte - analysis; Biological and medical sciences; Blood Cells - physiology; Cerebrospinal fluid; Cerebrospinal Fluid - cytology; Flow Cytometry; Fundamental and applied biological sciences. Psychology; Helper T cell; HIV Seropositivity - physiopathology; Homosexuality; Human immunodeficiency virus; human immunodeficiency virus 1; Humans; Male; Microbiology; Phenotype; Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains; Suppressor T cell; T cell; T-Lymphocytes - immunology; T-Lymphocytes - physiology; Virology; Flow cytometry; Suppressor T cell; Helper T cell; Human immunodeficiency virus; Cerebrospinal fluid; T cell; Human; Homosexuality; Antibody; Central nervous system; Retroviridae; Cell subpopulation; Blood; Virus; Numeration; T-Lymphocyte

Two-color flow cytometry was used to analyze T cell subsets (total (CD3), helper-inducer (CD4), and suppressor-cytotoxic (CD8)) in paired specimens of cerebrospinal fluid (CSF) and peripheral blood of 66 homosexual men, including 62 with antibodies to human immunodeficiency virus, type 1 (HIV-1). Wi...