Association between high polygenic risk scores and long-term exposure to air pollution in asthma development: a hospital-based case-control study - Chen, I-Chieh; Chen, Yi-Ming; Chen, Yun-Wen; Hsiao, Tzu-Hung; Yang, Hui-Wen; Tang, Kuo-Tung; Lin, Ching-Heng; Chu, Yu-Wen (Environmental health, 2025)
Keywords: Adult; Aged; Air Pollutants - adverse effects; Air Pollutants - analysis; Air pollution; Air Pollution - adverse effects; Air pollution effects; Allergic diseases; Asthma; Asthma - chemically induced; Asthma - epidemiology; Asthma - genetics; Biobanks; Case studies; Case-Control Studies; Chronic obstructive pulmonary disease; Dermatitis; Electronic health records; Environmental aspects; Environmental Exposure - adverse effects; Epidemiology; Exposure; Female; Genetic aspects; Genetic Risk Score; Genomes; Health aspects; Health care facilities; Health risk assessment; Health risks; Hospitals; Humans; Incidence; Inflammation; Long-term exposure; Low concentrations; Male; Medical records; Middle Aged; Multifactorial Inheritance; Multifactorial traits; Nitrogen dioxide; Particulate Matter; Patients; Pollutants; Polygenic risk score; Precision medicine; Quality control; Quartiles; Retrospective Studies; Rhinitis; Risk; Risk Factors; Scandals; Taiwan - epidemiology; Taiwan; United Kingdom--UK; Polygenic risk score; Long-term exposure; Air pollution; Asthma