Bicuculline blocks neuropeptide Y-induced phase advances when microinjected in the suprachiasmatic nucleus of syrian hamsters
Microinjection of neuropeptide Y (NPY) into the suprachiasmatic nucleus of the hypothalamus (SCN) during the middle of the subjective day (i.e. circadian time 6) causes large phase advances in circadian rhythms. The present study demonstrates that microinjection of the γ-aminobutyric acid (GABA) ant...
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| Published in | Brain research Vol. 675; no. 1; pp. 333 - 336 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
London
Elsevier B.V
27.03.1995
Amsterdam Elsevier New York, NY |
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| Abstract | Microinjection of neuropeptide Y (NPY) into the suprachiasmatic nucleus of the hypothalamus (SCN) during the middle of the subjective day (i.e. circadian time 6) causes large phase advances in circadian rhythms. The present study demonstrates that microinjection of the γ-aminobutyric acid (GABA) antagonist, bicuculline, completely blocks NPY-induced phase advances. These data indicate that GABA
A activity within the SCN may mediate the phase shifting effects of some stimuli on the circadian pacemaker. |
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| AbstractList | Microinjection of neuropeptide Y (NPY) into the suprachiasmatic nucleus of the hypothalamus (SCN) during the middle of the subjective day (i.e. circadian time 6) causes large phase advances in circadian rhythms. The present study demonstrates that microinjection of the γ-aminobutyric acid (GABA) antagonist, bicuculline, completely blocks NPY-induced phase advances. These data indicate that GABA
A activity within the SCN may mediate the phase shifting effects of some stimuli on the circadian pacemaker. Microinjection of neuropeptide Y (NPY) into the suprachiasmatic nucleus of the hypothalamus (SCN) during the middle of the subjective day (i.e. circadian time 6) causes large phase advances in circadian rhythms. The present study demonstrates that microinjection of the gamma-aminobutyric acid (GABA) antagonist, bicuculline, completely blocks NPY-induced phase advances. These data indicate that GABAA activity within the SCN may mediate the phase shifting effects of some stimuli on the circadian pacemaker. Microinjection of neuropeptide Y (NPY) into the suprachiasmatic nucleus of the hypothalamus (SCN) during the middle of the subjective day (i.e. circadian time 6) causes large phase advances in circadian rhythms. The present study demonstrates that microinjection of the gamma -aminobutyric acid (GABA) antagonist, bicuculline, completely blocks NPY-induced phase advances. These data indicate that GABA sub(A) activity within the SCN may mediate the phase shifting effects of some stimuli on the circadian pacemaker. |
| Author | Babagbemi, T.O. Albers, H.E. Huhman, K.L. |
| Author_xml | – sequence: 1 givenname: K.L. surname: Huhman fullname: Huhman, K.L. – sequence: 2 givenname: T.O. surname: Babagbemi fullname: Babagbemi, T.O. – sequence: 3 givenname: H.E. surname: Albers fullname: Albers, H.E. |
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| Keywords | GABA GABA A Circadian rhythm NPY Neuropeptide Y Suprachiasmatic nucleus Rodentia Central nervous system Biological rhythm Hypothalamus Vertebrata Mammalia Antagonist Gabaergic receptor A Hamster Brain (vertebrata) |
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| References | Swanson, Cowan, Jones (BIB21) 1974; 156 Rusak, Meijer, Harrington (BIB18) 1989; 493 Decavel, Van Den Pol (BIB5) 1990; 302 Turek, Losee-Olsen (BIB22) 1986; 321 Card, Moore (BIB3) 1989; 284 Saavedra, Palkovits, Brownstein, Axelrod (BIB19) 1974; 77 Smith, Inouye, Turek (BIB20) 1989; 164 Moore, Speh (BIB14) 1993; 150 in press. Moore, Lenn (BIB13) 1972; 146 Okamura, Berod, Julien, Geffard, Kitahama, Mallet, Bobillier (BIB15) 1989; 102 Ralph, Menaker (BIB17) 1989; 9 Daan, Pittendrigh (BIB4) 1976; 106 Harrington, Nance, Rusak (BIB8) 1985; 15 Ralph, Menaker (BIB16) 1986; 372 Hendrickson, Wagoner, Cowan (BIB9) 1972; 135 Huhman, K.L. and Albers, H.E., Neuropeptide Y microinjected into the suprachiasmatic region phase shifts circadian rhythms in constant darkness Francois-Bellan, Kachidian, Dusticier, Tonon, Vaudry, Bosler (BIB6) 1990; 19 Aghajanian, Bloom, Sheard (BIB1) 1969; 13 Fuxe (BIB7) 1965; 64 Johnson, Smale, Moore, Morin (BIB11) 1988; 85 Moore, Gustafson, Card (BIB12) 1984; 236 Albers, Ferris (BIB2) 1984; 50 Card (10.1016/0006-8993(95)00018-L_BIB3) 1989; 284 10.1016/0006-8993(95)00018-L_BIB10 Daan (10.1016/0006-8993(95)00018-L_BIB4) 1976; 106 Hendrickson (10.1016/0006-8993(95)00018-L_BIB9) 1972; 135 Rusak (10.1016/0006-8993(95)00018-L_BIB18) 1989; 493 Ralph (10.1016/0006-8993(95)00018-L_BIB16) 1986; 372 Ralph (10.1016/0006-8993(95)00018-L_BIB17) 1989; 9 Okamura (10.1016/0006-8993(95)00018-L_BIB15) 1989; 102 Turek (10.1016/0006-8993(95)00018-L_BIB22) 1986; 321 Moore (10.1016/0006-8993(95)00018-L_BIB12) 1984; 236 Moore (10.1016/0006-8993(95)00018-L_BIB13) 1972; 146 Fuxe (10.1016/0006-8993(95)00018-L_BIB7) 1965; 64 Smith (10.1016/0006-8993(95)00018-L_BIB20) 1989; 164 Harrington (10.1016/0006-8993(95)00018-L_BIB8) 1985; 15 Johnson (10.1016/0006-8993(95)00018-L_BIB11) 1988; 85 Aghajanian (10.1016/0006-8993(95)00018-L_BIB1) 1969; 13 Swanson (10.1016/0006-8993(95)00018-L_BIB21) 1974; 156 Albers (10.1016/0006-8993(95)00018-L_BIB2) 1984; 50 Saavedra (10.1016/0006-8993(95)00018-L_BIB19) 1974; 77 Francois-Bellan (10.1016/0006-8993(95)00018-L_BIB6) 1990; 19 Moore (10.1016/0006-8993(95)00018-L_BIB14) 1993; 150 Decavel (10.1016/0006-8993(95)00018-L_BIB5) 1990; 302 |
| References_xml | – volume: 13 start-page: 266 year: 1969 end-page: 273 ident: BIB1 article-title: Electron microscopy of degeneration within the serotonergic pathway of the rat publication-title: Brain Res. contributor: fullname: Sheard – volume: 493 start-page: 283 year: 1989 end-page: 291 ident: BIB18 article-title: Hamster circadian rhythms are phase-shifted by electrical stimulation of the geniculo-hypothalamic tract publication-title: Brain Res. contributor: fullname: Harrington – volume: 164 start-page: 805 year: 1989 end-page: 814 ident: BIB20 article-title: Central administration of muscimol phase-shifts the mammalian circadian clock publication-title: J. Comp. Physiol. contributor: fullname: Turek – volume: 85 start-page: 5301 year: 1988 end-page: 5304 ident: BIB11 article-title: Lateral geniculate lesions block circadian phase-shift responses to a benzodiazepine publication-title: Proc. Natl. Acad. Sci. USA contributor: fullname: Morin – volume: 102 start-page: 131 year: 1989 end-page: 136 ident: BIB15 article-title: Demonstration of GABAergic cell bodies in the suprachiasmatic nucleus: in situ hybridization of glutamic acid decarboxylase (GAD) mRNA and immunocytochemistry of GAD and GABA publication-title: Neurosci. Lett. contributor: fullname: Bobillier – volume: 15 start-page: 465 year: 1985 end-page: 472 ident: BIB8 article-title: Neuropeptide Y immunoreactivity in the hamster geniculo-suprachiasmatic tract publication-title: Brain Res. Bull. contributor: fullname: Rusak – volume: 106 start-page: 253 year: 1976 end-page: 266 ident: BIB4 article-title: A functional analysis of circadian pacemakers in nocturnal rodents. II. The variability of phase response curves publication-title: J. Comp. Physiol. contributor: fullname: Pittendrigh – volume: 9 start-page: 2858 year: 1989 end-page: 2865 ident: BIB17 article-title: GABA regulation of circadian responses to light. I. Involvement of GABA publication-title: J. Neurosci. contributor: fullname: Menaker – volume: 146 start-page: 1 year: 1972 end-page: 14 ident: BIB13 article-title: A retinohypothalamic projection in the rat publication-title: J. Comp. Neurol. contributor: fullname: Lenn – volume: 77 start-page: 157 year: 1974 end-page: 165 ident: BIB19 article-title: Serotonin distribution in the nuclei of the rat hypothalamus and preoptic region publication-title: Brain Res. contributor: fullname: Axelrod – volume: 50 start-page: 163 year: 1984 end-page: 168 ident: BIB2 article-title: Neuropeptide Y: role in light-dark cycle entrainment of hamster circadian rhythm publication-title: Neurosci. Lett. contributor: fullname: Ferris – volume: 284 start-page: 135 year: 1989 end-page: 147 ident: BIB3 article-title: Organization of lateral geniculate-hypothalamic connections in the rat publication-title: J. Comp. Neurol. contributor: fullname: Moore – volume: 64 start-page: 37 year: 1965 end-page: 85 ident: BIB7 article-title: Evidence of the existence of monoamine neurons in the central nervous system. IV. Distribution of monoamine nerve terminals in the central nervous system publication-title: Acta Physiol. Scand. contributor: fullname: Fuxe – volume: 236 start-page: 41 year: 1984 end-page: 46 ident: BIB12 article-title: Indentical immunoreactivity of afferents to the rat suprachiasmatic nucleus with antisera against avian pancreatic polypeptide, molluscan cardioexcitatory peptide and neuropeptide Y publication-title: Cell Tiss. Res. contributor: fullname: Card – volume: 19 start-page: 937 year: 1990 end-page: 947 ident: BIB6 article-title: GABA neurons in the rat suprachiasmatic nucleus: involvement in chemospecific synaptic circuitry and evidence for GAD-peptide colocalization publication-title: J. Neurocytol. contributor: fullname: Bosler – volume: 321 start-page: 167 year: 1986 end-page: 168 ident: BIB22 article-title: A benzodiazepine used in treatment of insomnia phase-shifts the mammalian circadian clock publication-title: Nature contributor: fullname: Losee-Olsen – volume: 135 start-page: 1 year: 1972 end-page: 26 ident: BIB9 article-title: An autoradiographic and electron microscopic study of retino-hypothalamic connections publication-title: Z. Zell. contributor: fullname: Cowan – volume: 150 start-page: 112 year: 1993 end-page: 116 ident: BIB14 article-title: GABA is the principal neurotransmitter of the circadian system publication-title: Neurosci. Lett. contributor: fullname: Speh – volume: 372 start-page: 405 year: 1986 end-page: 408 ident: BIB16 article-title: Effects of diazepam on circadian phase advances and delays publication-title: Brain Res. contributor: fullname: Menaker – volume: 302 start-page: 1019 year: 1990 end-page: 1037 ident: BIB5 article-title: GABA: a dominant neurotransmitter in the hypothalamus publication-title: J. Comp. Neurol. contributor: fullname: Van Den Pol – volume: 156 start-page: 143 year: 1974 end-page: 163 ident: BIB21 article-title: An autoradiographic study of the efferent connections of the ventral lateral geniculate nucleus in the albino rat and cat publication-title: J. Comp. Neurol. contributor: fullname: Jones – volume: 13 start-page: 266 year: 1969 ident: 10.1016/0006-8993(95)00018-L_BIB1 article-title: Electron microscopy of degeneration within the serotonergic pathway of the rat publication-title: Brain Res. doi: 10.1016/0006-8993(69)90286-8 contributor: fullname: Aghajanian – volume: 85 start-page: 5301 year: 1988 ident: 10.1016/0006-8993(95)00018-L_BIB11 article-title: Lateral geniculate lesions block circadian phase-shift responses to a benzodiazepine contributor: fullname: Johnson – volume: 19 start-page: 937 year: 1990 ident: 10.1016/0006-8993(95)00018-L_BIB6 article-title: GABA neurons in the rat suprachiasmatic nucleus: involvement in chemospecific synaptic circuitry and evidence for GAD-peptide colocalization publication-title: J. Neurocytol. doi: 10.1007/BF01186821 contributor: fullname: Francois-Bellan – volume: 64 start-page: 37 year: 1965 ident: 10.1016/0006-8993(95)00018-L_BIB7 article-title: Evidence of the existence of monoamine neurons in the central nervous system. IV. Distribution of monoamine nerve terminals in the central nervous system publication-title: Acta Physiol. Scand. contributor: fullname: Fuxe – volume: 135 start-page: 1 year: 1972 ident: 10.1016/0006-8993(95)00018-L_BIB9 article-title: An autoradiographic and electron microscopic study of retino-hypothalamic connections publication-title: Z. Zell. doi: 10.1007/BF00307084 contributor: fullname: Hendrickson – volume: 77 start-page: 157 year: 1974 ident: 10.1016/0006-8993(95)00018-L_BIB19 article-title: Serotonin distribution in the nuclei of the rat hypothalamus and preoptic region publication-title: Brain Res. doi: 10.1016/0006-8993(74)90812-9 contributor: fullname: Saavedra – volume: 321 start-page: 167 year: 1986 ident: 10.1016/0006-8993(95)00018-L_BIB22 article-title: A benzodiazepine used in treatment of insomnia phase-shifts the mammalian circadian clock publication-title: Nature doi: 10.1038/321167a0 contributor: fullname: Turek – volume: 102 start-page: 131 year: 1989 ident: 10.1016/0006-8993(95)00018-L_BIB15 article-title: Demonstration of GABAergic cell bodies in the suprachiasmatic nucleus: in situ hybridization of glutamic acid decarboxylase (GAD) mRNA and immunocytochemistry of GAD and GABA publication-title: Neurosci. Lett. doi: 10.1016/0304-3940(89)90067-0 contributor: fullname: Okamura – volume: 9 start-page: 2858 year: 1989 ident: 10.1016/0006-8993(95)00018-L_BIB17 article-title: GABA regulation of circadian responses to light. I. Involvement of GABAA-Benzodiazepine and GABAB receptors publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.09-08-02858.1989 contributor: fullname: Ralph – volume: 164 start-page: 805 year: 1989 ident: 10.1016/0006-8993(95)00018-L_BIB20 article-title: Central administration of muscimol phase-shifts the mammalian circadian clock publication-title: J. Comp. Physiol. doi: 10.1007/BF00616752 contributor: fullname: Smith – volume: 146 start-page: 1 year: 1972 ident: 10.1016/0006-8993(95)00018-L_BIB13 article-title: A retinohypothalamic projection in the rat publication-title: J. Comp. Neurol. doi: 10.1002/cne.901460102 contributor: fullname: Moore – volume: 372 start-page: 405 year: 1986 ident: 10.1016/0006-8993(95)00018-L_BIB16 article-title: Effects of diazepam on circadian phase advances and delays publication-title: Brain Res. doi: 10.1016/0006-8993(86)91154-6 contributor: fullname: Ralph – ident: 10.1016/0006-8993(95)00018-L_BIB10 doi: 10.1016/0196-9781(94)90126-0 – volume: 106 start-page: 253 year: 1976 ident: 10.1016/0006-8993(95)00018-L_BIB4 article-title: A functional analysis of circadian pacemakers in nocturnal rodents. II. The variability of phase response curves publication-title: J. Comp. Physiol. doi: 10.1007/BF01417857 contributor: fullname: Daan – volume: 15 start-page: 465 year: 1985 ident: 10.1016/0006-8993(95)00018-L_BIB8 article-title: Neuropeptide Y immunoreactivity in the hamster geniculo-suprachiasmatic tract publication-title: Brain Res. Bull. doi: 10.1016/0361-9230(85)90037-1 contributor: fullname: Harrington – volume: 150 start-page: 112 year: 1993 ident: 10.1016/0006-8993(95)00018-L_BIB14 article-title: GABA is the principal neurotransmitter of the circadian system publication-title: Neurosci. Lett. doi: 10.1016/0304-3940(93)90120-A contributor: fullname: Moore – volume: 302 start-page: 1019 year: 1990 ident: 10.1016/0006-8993(95)00018-L_BIB5 article-title: GABA: a dominant neurotransmitter in the hypothalamus publication-title: J. Comp. Neurol. doi: 10.1002/cne.903020423 contributor: fullname: Decavel – volume: 493 start-page: 283 year: 1989 ident: 10.1016/0006-8993(95)00018-L_BIB18 article-title: Hamster circadian rhythms are phase-shifted by electrical stimulation of the geniculo-hypothalamic tract publication-title: Brain Res. doi: 10.1016/0006-8993(89)91163-3 contributor: fullname: Rusak – volume: 284 start-page: 135 year: 1989 ident: 10.1016/0006-8993(95)00018-L_BIB3 article-title: Organization of lateral geniculate-hypothalamic connections in the rat publication-title: J. Comp. Neurol. doi: 10.1002/cne.902840110 contributor: fullname: Card – volume: 156 start-page: 143 year: 1974 ident: 10.1016/0006-8993(95)00018-L_BIB21 article-title: An autoradiographic study of the efferent connections of the ventral lateral geniculate nucleus in the albino rat and cat publication-title: J. Comp. Neurol. doi: 10.1002/cne.901560203 contributor: fullname: Swanson – volume: 50 start-page: 163 year: 1984 ident: 10.1016/0006-8993(95)00018-L_BIB2 article-title: Neuropeptide Y: role in light-dark cycle entrainment of hamster circadian rhythm publication-title: Neurosci. Lett. doi: 10.1016/0304-3940(84)90480-4 contributor: fullname: Albers – volume: 236 start-page: 41 year: 1984 ident: 10.1016/0006-8993(95)00018-L_BIB12 article-title: Indentical immunoreactivity of afferents to the rat suprachiasmatic nucleus with antisera against avian pancreatic polypeptide, molluscan cardioexcitatory peptide and neuropeptide Y publication-title: Cell Tiss. Res. doi: 10.1007/BF00216511 contributor: fullname: Moore |
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| SubjectTerms | Animals Bicuculline - administration & dosage Bicuculline - pharmacology Biological and medical sciences Chronobiology Circadian rhythm Cricetinae Fundamental and applied biological sciences. Psychology GABA GABA A GABA-A Receptor Antagonists Male Mesocricetus Mesocricetus auratus Microinjections Neuropeptide Y - antagonists & inhibitors Neuropeptide Y - pharmacology NPY Receptors, GABA-A - metabolism Regression Analysis Suprachiasmatic Nucleus - metabolism Suprachiasmatic Nucleus - physiology Vertebrates: anatomy and physiology, studies on body, several organs or systems |
| Title | Bicuculline blocks neuropeptide Y-induced phase advances when microinjected in the suprachiasmatic nucleus of syrian hamsters |
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