Acute and persistent effects of methamphetamine on developing monoaminergic neurons in reaggregate tissue culture

• Published in: Brain research Vol. 575; no. 1; p. 6
• Main Authors: Won, L, Kontur, P J, Choi, H K, Hoffmann, P C, Heller, B, Heller, A
• Format: Journal Article
• Language: English
• Published: Netherlands 13.03.1992
• Subjects: Animals; Culture Techniques; Dopamine - metabolism; Methamphetamine - toxicity; Mice; Neurons - drug effects; Neurons - metabolism; Serotonin - metabolism; Time Factors

Three-dimensional, rotation-mediated reaggregate tissue cultures composed of rostral mesencephalic cells and corpus striatal cells were used to examine the short-term and persistent effects of methamphetamine on developing monoamine-containing neurons. Reaggregates were exposed to drug for one week....