Bacterial cellulose membranes as drug delivery systems: An in vivo skin compatibility study

• Published in: European journal of pharmaceutics and biopharmaceutics Vol. 86; no. 3; pp. 332 - 336
• Main Authors: Almeida, I.F., Pereira, T., Silva, N.H.C.S., Gomes, F.P., Silvestre, A.J.D., Freire, C.S.R., Sousa Lobo, J.M., Costa, P.C.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.04.2014
• Subjects: Adult; Bacteria; Bacterial cellulose; Cellulose - administration & dosage; Cellulose - chemistry; Drug delivery; Drug Delivery Systems - methods; Female; Gluconacetobacter - chemistry; Gluconoacetobacter sacchari; Humans; Male; Skin - drug effects; Skin - metabolism; Skin compatibility; Skin hydration; Skin irritation; Young Adult; Skin irritation; Bacterial cellulose; Drug delivery; Skin compatibility; Gluconoacetobacter sacchari; Skin hydration

Bacterial cellulose (BC) is a highly pure form of cellulose, produced in the form of a swollen membrane by several bacteria that demonstrated to be able to modulate the skin release of model drugs. In the present study, the skin irritation potential of BC was evaluated in human subjects. BC membrane...