Aurora A and NF-κB Survival Pathway Drive Chemoresistance in Acute Myeloid Leukemia via the TRAF-Interacting Protein TIFA - Wei, Tong-You Wade; Wu, Pei-Yu; Wu, Ting-Jung; Hou, Hsin-An; Chou, Wen-Chien; Teng, Chieh-Lin Jerry; Lin, Chih-Ru; Chen, Jo-Mei Maureen; Lin, Ting-Yang; Su, Hsiang-Chun; Huang, Chia-Chi Flora; Yu, Chang-Tze Ricky; et al. (Cancer research (Chicago, Ill.), 2017)
Keywords: Acute myeloid leukemia; Adaptor Proteins, Signal Transducing - metabolism; Animals; Apoptosis; Aurora Kinase A - metabolism; Bcl-2 protein; Bcl-x protein; Blotting, Western; Bone marrow; Cancer; Cell Line, Tumor; Chemoresistance; Disease Progression; Disease-Free Survival; Drug Resistance, Neoplasm - physiology; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorescent Antibody Technique; Gene Knockdown Techniques; Heterografts; Humans; Immunoprecipitation; Kaplan-Meier Estimate; Leukemia; Leukemia, Myeloid, Acute - mortality; Leukemia, Myeloid, Acute - pathology; Medical prognosis; Mice; Myeloid leukemia; NF-kappa B - metabolism; NF-κB protein; Phosphorylation; Prognosis; Proportional Hazards Models; Proteins; Rodents; Signal transduction; Signal Transduction - physiology; Xenografts