Folic acid deficiency enhanced microglial immune response via the Notch1/nuclear factor kappa B p65 pathway in hippocampus following rat brain I/R injury and BV2 cells - Cheng, Man; Yang, Liu; Dong, Zhiping; Wang, Mengying; Sun, Yan; Liu, Huan; Wang, Xuan; Sai, Na; Huang, Guowei; Zhang, Xumei (Journal of cellular and molecular medicine, 2019)
Keywords: Acids; Alzheimer's disease; Animals; Brain; Brain Injuries - complications; Brain Injuries - metabolism; Brain Injuries - pathology; Brain injury; Brain Ischemia - complications; Brain Ischemia - metabolism; Brain Ischemia - pathology; Carotid arteries; Cell death; Cell Line; Cerebral blood flow; Cytokines; Cytokines - metabolism; Dentate gyrus; Dipeptides - pharmacology; Experiments; Folic acid; Folic Acid Deficiency - immunology; Glucose - deficiency; Hippocampus; Hippocampus - metabolism; Hypoxia; Immune response; Infarction, Middle Cerebral Artery - complications; Inflammation; Inflammation - pathology; inflammatory; ischaemia‐reperfusion; Ischemia; Male; Mice; Microglia; Microglia - drug effects; Microglia - immunology; microglial; Neurons - drug effects; Neurons - pathology; Notch pathway; Notch1 protein; Nuclear transport; Original; Oxygen; Phenylglycine; Phosphorylation; Rats, Sprague-Dawley; Receptor, Notch1 - metabolism; Reperfusion; Signal Transduction - drug effects; Stroke; Studies; Transcription Factor RelA - metabolism; Tumor necrosis factor; Tumor necrosis factor-TNF; Tumors; Vitamin B; Vitamin deficiency; China; Notch pathway; microglial; ischaemia-reperfusion; hippocampus; folic acid; inflammatory