Age-related changes in the glutathione redox system

• Published in: Cell biochemistry and function Vol. 20; no. 1; pp. 61 - 66
• Main Authors: Erden-İnal, Mine, Sunal, Emine, Kanbak, Güngör
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.03.2002
• Subjects: Adolescent; Adult; Aged; aging; Aging - blood; antioxidant enzymes; Antioxidants - metabolism; Child; Child, Preschool; Erythrocytes - enzymology; Erythrocytes - metabolism; Female; glutathione; Glutathione - blood; Glutathione Peroxidase - metabolism; Glutathione Reductase - metabolism; Humans; Infant; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; selenium; Selenium - blood

The effect of aging on the glutathione redox system was evaluated in this study. For this purpose, we determined reduced glutathione (GSH) and oxidized glutathione (GSSG) in whole blood, glutathione peroxidase (GPx) and glutathione reductase (GSSGR) in erythrocytes and selenium (Se) in plasma in 176...