Association of baseline vitamin D level with genetic determinants and virologic response in patients with chronic hepatitis B

• Published in: Hepatology research Vol. 48; no. 3; pp. E213 - E221
• Main Authors: Yu, Rui, Tan, Deming, Ning, Qin, Niu, Junqi, Bai, Xuefan, Chen, Shijun, Cheng, Jun, Yu, Yanyan, Wang, Hao, Xu, Min, Shi, Guangfeng, Wan, Mobin, Chen, Xinyue, Tang, Hong, Sheng, Jifang, Dou, Xiaoguang, Shi, Junping, Ren, Hong, Wang, Maorong, Zhang, Hongfei, Gao, Zhiliang, Chen, Chengwei, Ma, Hong, Jia, Jidong, Hou, Jinlin, Xie, Qing, Sun, Jian
• Format: Journal Article
• Language: English
• Published: Netherlands Wiley Subscription Services, Inc 01.02.2018
• Subjects: 7-Dehydrocholesterol reductase; Alanine; Alanine transaminase; Deoxyribonucleic acid; DNA; Gene polymorphism; genetic determinants; Hepatitis; Hepatitis B; Hepatitis B e antigen; Latitude; Multivariate analysis; Seroconversion; treatment response; Vitamin D; Vitamin deficiency; hepatitis B; treatment response; vitamin D; genetic determinants; latitude

Aim The role of vitamin D in individuals with chronic hepatitis B (CHB) is unclear. We aimed to explore the association of baseline vitamin D level with genetic determinants and week‐104 treatment outcome in CHB patients. Methods Baseline serum 25‐hydroxycholecalciferol (25(OH)D) levels and genetic...