The Benefits of Intensive Versus Standard Blood Pressure Treatment According to Fine Particulate Matter Air Pollution Exposure: A Post Hoc Analysis of SPRINT

• Published in: Hypertension (Dallas, Tex. 1979) Vol. 77; no. 3; pp. 813 - 822
• Main Authors: Al-Kindi, Sadeer G., Brook, Robert D., Bhatt, Udayan, Brauer, Michael, Cushman, William C., Hanson, Heidi A., Kostis, John, Lash, James P., Paine, Robert, Raphael, Kalani L., Rapp, Stephen, Tamariz, Leonardo, Wright, Jackson T., Rajagopalan, Sanjay
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 03.03.2021
• Subjects: Aged; Air Pollutants - analysis; Antihypertensive Agents - therapeutic use; Cardiovascular Diseases - etiology; Cardiovascular Diseases - physiopathology; Cardiovascular Diseases - prevention & control; Clinical Trials as Topic; Environmental Exposure - adverse effects; Female; Humans; Hypertension - drug therapy; Hypertension - etiology; Hypertension - physiopathology; Male; Middle Aged; Outcome Assessment, Health Care - methods; Outcome Assessment, Health Care - statistics & numerical data; Particulate Matter - analysis; Proportional Hazards Models; Risk Factors; blood pressure; particulate matter; air pollution; cardiovascular diseases; hypertension

Fine particulate matter <2.5 µm (PM2.5) air pollution is implicated in global mortality, especially from cardiovascular causes. A large body of evidence suggests a link between PM2.5 and elevation in blood pressure (BP), with the latter implicated as a potential mediator of cardiovascular events....