Adenosine triphosphate concentration of exhaled breath condensate in asthma

• Published in: Chest Vol. 138; no. 3; p. 536
• Main Authors: Lázár, Zsófia, Cervenak, László, Orosz, Márta, Gálffy, Gabriella, Komlósi, Zsolt I, Bikov, András, Losonczy, György, Horváth, Ildikó
• Format: Journal Article
• Language: English
• Published: United States 01.09.2010
• Subjects: Adenosine Triphosphate - metabolism; Adult; Airway Resistance; Asthma - diagnosis; Asthma - metabolism; Asthma - physiopathology; Biomarkers - metabolism; Breath Tests; Bronchoalveolar Lavage Fluid; Case-Control Studies; Cross-Sectional Studies; Exhalation; Extravascular Lung Water - metabolism; Female; Humans; Male; Middle Aged; Young Adult

Purinergic signaling is involved in asthma pathogenesis. Not only adenosine but also adenosine triphosphate (ATP) might play a role, but human evidence is scarce. ATP can be measured in exhaled breath condensate (EBC), a noninvasive airway sample suggested as being suitable for patient monitoring. W...