Safety, Pharmacokinetics, and Efficacy of CPX-1 Liposome Injection in Patients with Advanced Solid Tumors - Batist, Gerald; Gelmon, Karen A.; Chi, Kim N.; Miller, Wilson H.; Chia, Stephen K.L.; Mayer, Lawrence D.; Swenson, Christine E.; Janoff, Andrew S.; Louie, Arthur C. (Clinical cancer research, 2009)
Keywords: Adult; Aged; Antineoplastic agents; Antineoplastic Agents - pharmacokinetics; Antineoplastic Agents - therapeutic use; Area Under Curve; Biological and medical sciences; Camptothecin - administration & dosage; Camptothecin - analogs & derivatives; Camptothecin - pharmacology; Cohort Studies; combination chemotherapy; Dose-Response Relationship, Drug; Female; Floxuridine - administration & dosage; Floxuridine - pharmacology; Humans; Liposomes - chemistry; Male; Maximum Tolerated Dose; Medical sciences; Middle Aged; molar ratios; Multiple tumors. Solid tumors. Tumors in childhood (general aspects); Neoplasms - therapy; Pharmacology. Drug treatments; Phase 1; Treatment Outcome; Tumors; Human; Solid tumor; Toxicity; Treatment efficiency; Liposome; Patient; Advanced stage; Drug carrier; Malignant tumor; Safety; Pharmacokinetics; Cancer