Exploring the Link Between C‐Reactive Protein Change and Stroke Risk: Insights From a Prospective Cohort Study and Genetic Evidence

• Published in: Journal of the American Heart Association Vol. 14; no. 7; p. e038086
• Main Authors: Ling, Yitong, Yuan, Shiqi, Cheng, Hongtao, Tan, Shanyuan, Huang, Xiaxuan, Tang, Yonglan, Bai, Zihong, Li, Rui, Li, Li, Li, Shuna, Huang, Liying, Xu, Anding, Lyu, Jun
• Format: Journal Article
• Language: English
• Published: England John Wiley and Sons Inc 01.04.2025; Wiley
• Subjects: Aged; Biomarkers - blood; C-Reactive Protein - analysis; C-Reactive Protein - genetics; C-Reactive Protein - metabolism; C‐reactive protein change; Female; genetic analyses; Genome-Wide Association Study; Humans; Ischemic Stroke - blood; Ischemic Stroke - diagnosis; Ischemic Stroke - epidemiology; Ischemic Stroke - genetics; Male; Middle Aged; Original Research; Prospective Studies; Risk Assessment; Risk Factors; stroke; Stroke - blood; Stroke - epidemiology; Stroke - genetics; United Kingdom - epidemiology; United Kingdom; stroke; C‐reactive protein change; genetic analyses

Previous research on how changes in CRP (C-reactive protein) levels predict stroke risk is limited. This study aimed to examine the association between CRP change and the risk of stroke and its subtypes. Based on the UK Biobank data, we investigated the association between CRP change and the risk of...