Fluorescent Conjugates Based on Prostate-Specific Membrane Antigen Ligands as an Effective Visualization Tool for Prostate Cancer

• Published in: Biochemistry (Moscow) Vol. 88; no. 7; pp. 953 - 967
• Main Authors: Uspenskaia, Anastasiia A., Krasnikov, Pavel A., Beloglazkina, Elena K., Machulkin, Aleksei E.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01.07.2023; Springer; Springer Nature B.V
• Subjects: Analysis; Antigens; Biochemistry; Biomarkers; Biomedical and Life Sciences; Biomedicine; Bioorganic Chemistry; Cancer therapies; Conjugates; Diagnosis; Diagnostics; Dyes; Fluorescent dyes; Fluorescent indicators; Histopathology; Identification and classification; Life Sciences; Ligands; Membranes; Microbiology; Molecular structure; Prostate cancer; Prostate-specific antigen; Proteins; Review; Urea; Russia; targeted drug delivery; prostate cancer; PSMA; fluorescent dyes; prostate-specific membrane antigen

Fluorescent dyes are widely used in histological studies and in intraoperative imaging, including surgical treatment of prostate cancer (PC), which is one of the most common types of cancerous tumors among men today. Targeted delivery of fluorescent conjugates greatly improves diagnostic efficiency...