The use of cholinesterase inhibitors and the risk of myocardial infarction and death: a nationwide cohort study in subjects with Alzheimer's disease

• Published in: European heart journal Vol. 34; no. 33; pp. 2585 - 2591
• Main Authors: Nordström, Peter, Religa, Dorota, Wimo, Anders, Winblad, Bengt, Eriksdotter, Maria
• Format: Journal Article
• Language: English
• Published: England 01.09.2013
• Subjects: Adult; Aged; Aged, 80 and over; Alzheimer Disease - drug therapy; Alzheimer Disease - mortality; Alzheimers dementia; choline esterase inhibitors; Cholinesterase Inhibitors - therapeutic use; Cohort Studies; Female; Humans; Male; Middle Aged; myocardial infarction; Myocardial Infarction - mortality; Myocardial Infarction - prevention & control; Risk Factors; Survival Analysis; Myocardial infarction; Choline esterase inhibitors; Alzheimer's dementia

Cholinesterase inhibitors (ChEIs) are used for symptomatic treatment of Alzheimer's disease. These drugs have vagotonic and anti-inflammatory properties that could be of interest also with respect to cardiovascular disease. This study evaluated the use of ChEIs and the later risk of myocardial...