The combined status of ATM and p53 link tumor development with therapeutic response - Jiang, Hai; Reinhardt, H. Christian; Bartkova, Jirina; Tommiska, Johanna; Blomqvist, Carl; Nevanlinna, Heli; Bartek, Jiri; Yaffe, Michael B.; Hemann, Michael T. (Genes & development, 2009)
Keywords: Animals; Antineoplastic Agents - pharmacology; Antineoplastic Agents - therapeutic use; Apoptosis - drug effects; Ataxia Telangiectasia Mutated Proteins; ATM; Breast Neoplasms - drug therapy; Breast Neoplasms - physiopathology; Cancer; Cell Cycle Proteins - metabolism; Cell Line, Tumor; Checkpoint Kinase 2; chemotherapy; DNA-Binding Proteins - deficiency; DNA-Binding Proteins - metabolism; DNA-PK; Drug Resistance, Neoplasm; Female; Humans; MEDICIN; MEDICINE; Mice; Mice, Nude; mouse models; Neoplasms - drug therapy; Neoplasms - physiopathology; NIH 3T3 Cells; p53; Protein-Serine-Threonine Kinases - deficiency; Protein-Serine-Threonine Kinases - metabolism; Research Paper; Signal Transduction; Survival Analysis; Tumor Suppressor Protein p53 - metabolism; Tumor Suppressor Proteins - deficiency; Tumor Suppressor Proteins - metabolism