Dengue virus infection – a review of pathogenesis, vaccines, diagnosis and therapy

• Published in: Virus research Vol. 324; p. 199018
• Main Authors: Kok, Boon Hui, Lim, Hui Ting, Lim, Chin Peng, Lai, Ngit Shin, Leow, Chiuan Yee, Leow, Chiuan Herng
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.01.2023
• Subjects: Animals; Antibodies, Neutralizing; Antibodies, Viral - therapeutic use; Cross reaction; Dengue - diagnosis; Dengue - prevention & control; Dengue Vaccines; Dengue Virus; DENV; Development; Diagnostic; Humans; Therapeutic; Vaccines; Development; Therapeutic; Diagnostic; DENV; Cross reaction

•Reviews on unsolved issues of DENV from different perspectives such as the effect of antibody dependent enhancement, immune escape and limitations of commercial diagnostic kits.•Case studies on variety of potential therapeutic candidates targeting on DENV such as peptide inhibitors, broadly neutral...