Investigation of decision-making under uncertainty in healthy subjects: A multi-centric fMRI study

• Published in: Behavioural brain research Vol. 261; pp. 89 - 96
• Main Authors: Krug, A., Cabanis, M., Pyka, M., Pauly, K., Walter, H., Landsberg, M., Shah, N. Jon, Winterer, G., Wölwer, W., Musso, F., Müller, B.W., Wiedemann, G., Herrlich, J., Schnell, K., Vogeley, K., Schilbach, L., Langohr, K., Rapp, A., Klingberg, S., Kircher, T.
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier B.V 15.03.2014; Elsevier
• Subjects: ACC; Adult; Behavioral psychophysiology; Biological and medical sciences; Cerebral Cortex - blood supply; Cerebral Cortex - physiology; Decision Making - physiology; Decision-making; Female; fMRI; Fundamental and applied biological sciences. Psychology; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Oxygen - blood; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Psychomotor Performance - physiology; Uncertainty; Vertebrates: nervous system and sense organs; Decision-making; fMRI; ACC; Uncertainty; Human; Healthy subject; Decision making; Nuclear magnetic resonance imaging; Functional imaging

•Sixty-four healthy subjects in a multi-centric fMRI study.•Information gathering was correlated with a network of prefrontal and parietal cortex.•Reaching a decision was correlated with medial prefrontal cortex and precuneus.•Uncertainty acceptance activated a network of the frontal cortex and insu...