Effects of naphthenic acid exposure on development and liver metabolic processes in anuran tadpoles

• Published in: Environmental pollution (1987) Vol. 177; pp. 22 - 27
• Main Authors: Melvin, Steven D., Lanctôt, Chantal M., Craig, Paul M., Moon, Thomas W., Peru, Kerry M., Headley, John V., Trudeau, Vance L.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.06.2013; Elsevier
• Subjects: Amphibian; Animal, plant and microbial ecology; Animals; Anura - growth & development; Applied ecology; aquatic environment; Biological and medical sciences; Carboxylic Acids - toxicity; cholesterol; Chronic exposure; condition factor; Development; Ecotoxicology, biological effects of pollution; Effects of pollution and side effects of pesticides on vertebrates; energy metabolism; Female; Fundamental and applied biological sciences. Psychology; glucose; glycogen; glycolysis; guidelines; hepatotoxicity; industrial applications; Larva - growth & development; Larva - metabolism; Lithobates; liver; Liver - drug effects; Liver - metabolism; liver function; Male; Metabolic disruption; naphthenates; Naphthenic acid; oil sands; Reptilia. Amphibia; Tadpoles; triacylglycerols; wastewater; Water Pollutants, Chemical - toxicity; Development; Metabolic disruption; Naphthenic acid; Tadpoles; Amphibian; Chronic exposure; Growth; Toxicity; Liver; Amphibia; Rana pipiens; Salientia; Liver function; Vertebrata; Chronic; Sublethal dose; Larva; Carboxylic acid; Animal; Ranidae; Hepatotoxicity; Organic compounds

Naphthenic acids (NA) are used in a variety of commercial and industrial applications, and are primary toxic components of oil sands wastewater. We investigated developmental and metabolic responses of tadpoles exposed to sub-lethal concentrations of a commercial NA blend throughout development. We...