The Clinical Relevance and Functional Implications of Thymosin Beta-10 in Glioma

• Published in: Genetics Research Vol. 2023; pp. 5517445 - 13
• Main Authors: Li, Weimin, Chen, Jinliang, Xiang, Chengwei, Long, Yong, Wu, Ke, Li, Juan
• Format: Journal Article
• Language: English
• Published: England Hindawi 2023; Hindawi Limited; Wiley
• Subjects: Age; Biomarkers; Brain; Brain cancer; Brain Neoplasms - genetics; Brain Neoplasms - pathology; Brain tumors; Cells; Clinical outcomes; Clinical Relevance; Correlation; Dendritic cells; Ethics; Experiments; Gender; Glioma; Glioma - genetics; Glioma - pathology; Glioma cells; Humans; Immune system; Infiltration; Leukocytes (neutrophilic); Lymphocytes; Lymphocytes T; Macrophages; Medical prognosis; Metastases; Patients; Prognosis; Survival; Survival Analysis; Therapeutic targets; Thymosin - genetics; Thymosin - metabolism; Tumor Microenvironment; Tumors; Xenotransplantation

Glioma is a highly aggressive form of brain cancer characterized by limited treatment options and poor patient prognosis. In this study, we aimed to elucidate the oncogenic role of thymosin beta-10 (TMSB10) in glioma through comprehensive analyses of patient data from the TCGA and GTEx databases. Ou...