Efficacy of argyrophilic nucleolar organizing region analysis using computer-assisted and manual in oral leukoplakia: A comparative study

• Published in: Indian journal of cancer Vol. 52; no. 1; p. 75
• Main Authors: Garg, Kavita Nitish, Raj, Vineet, Chandra, Shaleen
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.01.2015; Medknow Publications & Media Pvt. Ltd
• Subjects: Antigens, Nuclear - biosynthesis; Antigens, Nuclear - genetics; Care and treatment; Cell Proliferation - genetics; Development and progression; Epithelium - pathology; Evaluation; Female; Humans; Image Processing, Computer-Assisted; Leukoplakia; Leukoplakia, Oral - diagnosis; Leukoplakia, Oral - genetics; Leukoplakia, Oral - pathology; Male; Medical computer applications; Molecular Imaging; Mouth Neoplasms - diagnosis; Mouth Neoplasms - genetics; Mouth Neoplasms - pathology; Precision medicine; Technology application

Nucleolar organizer regions are loops of DNA containing ribosomal RNA genes and presumably are associated with ribosomal RNA activity, protein synthesis, and cell proliferation. Argyrophilic nucleolar organizer region (AgNOR) count has been suggested as an objective method in differentiating dysplas...