Multiple sclerosis lesions affect intrinsic functional connectivity of the spinal cord

• Published in: Brain (London, England : 1878) Vol. 141; no. 6; pp. 1650 - 1664
• Main Authors: Conrad, Benjamin N, Barry, Robert L, Rogers, Baxter P, Maki, Satoshi, Mishra, Arabinda, Thukral, Saakshi, Sriram, Subramaniam, Bhatia, Aashim, Pawate, Siddharama, Gore, John C, Smith, Seth A
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.06.2018
• Subjects: Original; functional connectivity; spinal cord; lesions; multiple sclerosis; resting state functional magnetic resonance imaging

Multiple sclerosis is associated with spinal cord lesions and dysfunction. Using resting-state fMRI to assess cervical spinal cord networks, Conrad et al. report that average connectivity strength is not significantly different in patients compared to controls. However, lesions are associated with a...