Fluorogenic Probing of Specific Recognitions between Sugar Ligands and Glycoprotein Receptors on Cancer Cells by an Economic Graphene Nanocomposite

• Published in: Advanced materials (Weinheim) Vol. 25; no. 30; pp. 4097 - 4101
• Main Authors: Zhang, Hai-Lin, Wei, Xiao-Li, Zang, Yi, Cao, Jia-Yi, Liu, Shanshan, He, Xiao-Peng, Chen, Qibin, Long, Yi-Tao, Li, Jia, Chen, Guo-Rong, Chen, Kaixian
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 14.08.2013; WILEY‐VCH Verlag
• Subjects: Carbohydrate Metabolism; click chemistry; Economics; glycoprotein receptor; Glycoproteins - metabolism; Graphene; Graphite - chemistry; Hep G2 Cells; Humans; Microscopy, Fluorescence - methods; Molecular Probe Techniques; Nanocomposites; Nanomaterials; Nanoparticles - chemistry; Nanostructure; Oxides; Receptors; Receptors, Cell Surface - metabolism; Recognition; rhodamine; Rhodamines - chemistry; sugar; glycoprotein receptor; click chemistry; sugar; graphene; rhodamine

Economical nanocomposites based on π‐stacking of N‐acetyl glycosyl rhodamine B to graphene oxide (GO) are simply prepared. These “sweet” GO‐materials are proven to be admirable for the fluorogenic recognition of specific intercellular sugar‐based ligand‐glycoprotein receptor interactions of interest...