Fluorogenic Probing of Specific Recognitions between Sugar Ligands and Glycoprotein Receptors on Cancer Cells by an Economic Graphene Nanocomposite

Economical nanocomposites based on π‐stacking of N‐acetyl glycosyl rhodamine B to graphene oxide (GO) are simply prepared. These “sweet” GO‐materials are proven to be admirable for the fluorogenic recognition of specific intercellular sugar‐based ligand‐glycoprotein receptor interactions of interest...

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Published in	Advanced materials (Weinheim) Vol. 25; no. 30; pp. 4097 - 4101
Main Authors	Zhang, Hai-Lin, Wei, Xiao-Li, Zang, Yi, Cao, Jia-Yi, Liu, Shanshan, He, Xiao-Peng, Chen, Qibin, Long, Yi-Tao, Li, Jia, Chen, Guo-Rong, Chen, Kaixian
Format	Journal Article
Language	English
Published	Weinheim WILEY-VCH Verlag 14.08.2013 WILEY‐VCH Verlag
Subjects	Carbohydrate Metabolism click chemistry Economics glycoprotein receptor Glycoproteins - metabolism Graphene Graphite - chemistry Hep G2 Cells Humans Microscopy, Fluorescence - methods Molecular Probe Techniques Nanocomposites Nanomaterials Nanoparticles - chemistry Nanostructure Oxides Receptors Receptors, Cell Surface - metabolism Recognition rhodamine Rhodamines - chemistry sugar glycoprotein receptor click chemistry sugar graphene rhodamine
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Abstract	Economical nanocomposites based on π‐stacking of N‐acetyl glycosyl rhodamine B to graphene oxide (GO) are simply prepared. These “sweet” GO‐materials are proven to be admirable for the fluorogenic recognition of specific intercellular sugar‐based ligand‐glycoprotein receptor interactions of interest.
AbstractList	Economical nanocomposites based on π-stacking of N-acetyl glycosyl rhodamine B to graphene oxide (GO) are simply prepared. These "sweet" GO-materials are proven to be admirable for the fluorogenic recognition of specific intercellular sugar-based ligand-glycoprotein receptor interactions of interest. Economical nanocomposites based on π-stacking of N-acetyl glycosyl rhodamine B to graphene oxide (GO) are simply prepared. These "sweet" GO-materials are proven to be admirable for the fluorogenic recognition of specific intercellular sugar-based ligand-glycoprotein receptor interactions of interest.Economical nanocomposites based on π-stacking of N-acetyl glycosyl rhodamine B to graphene oxide (GO) are simply prepared. These "sweet" GO-materials are proven to be admirable for the fluorogenic recognition of specific intercellular sugar-based ligand-glycoprotein receptor interactions of interest. Economical nanocomposites based on pi -stacking of N-acetyl glycosyl rhodamine B to graphene oxide (GO) are simply prepared. These "sweet" GO-materials are proven to be admirable for the fluorogenic recognition of specific intercellular sugar-based ligand-glycoprotein receptor interactions of interest.
Author	Cao, Jia-Yi Long, Yi-Tao Wei, Xiao-Li Chen, Guo-Rong Li, Jia Zhang, Hai-Lin Chen, Qibin Liu, Shanshan Zang, Yi He, Xiao-Peng Chen, Kaixian
Author_xml	– sequence: 1 givenname: Hai-Lin surname: Zhang fullname: Zhang, Hai-Lin organization: Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, P.R. China – sequence: 2 givenname: Xiao-Li surname: Wei fullname: Wei, Xiao-Li organization: Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, P.R. China – sequence: 3 givenname: Yi surname: Zang fullname: Zang, Yi organization: National Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, 189 Guo Shoujing Rd., Shanghai 201203, P.R. China – sequence: 4 givenname: Jia-Yi surname: Cao fullname: Cao, Jia-Yi organization: Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, P.R. China – sequence: 5 givenname: Shanshan surname: Liu fullname: Liu, Shanshan organization: Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, P.R. China – sequence: 6 givenname: Xiao-Peng surname: He fullname: He, Xiao-Peng email: xphe@ecust.edu.cn organization: Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, P.R. China – sequence: 7 givenname: Qibin surname: Chen fullname: Chen, Qibin organization: Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, P.R. China – sequence: 8 givenname: Yi-Tao surname: Long fullname: Long, Yi-Tao organization: Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, P.R. China – sequence: 9 givenname: Jia surname: Li fullname: Li, Jia email: jli@mail.shcnc.ac.cn organization: National Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, 189 Guo Shoujing Rd., Shanghai 201203, P.R. China – sequence: 10 givenname: Guo-Rong surname: Chen fullname: Chen, Guo-Rong email: mrs_guorongchen@ecust.edu.cn organization: Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, P.R. China – sequence: 11 givenname: Kaixian surname: Chen fullname: Chen, Kaixian organization: Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, P.R. China
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Keywords	glycoprotein receptor click chemistry sugar graphene rhodamine
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Snippet	Economical nanocomposites based on π‐stacking of N‐acetyl glycosyl rhodamine B to graphene oxide (GO) are simply prepared. These “sweet” GO‐materials are... Economical nanocomposites based on π-stacking of N-acetyl glycosyl rhodamine B to graphene oxide (GO) are simply prepared. These "sweet" GO-materials are... Economical nanocomposites based on pi -stacking of N-acetyl glycosyl rhodamine B to graphene oxide (GO) are simply prepared. These "sweet" GO-materials are...
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SubjectTerms	Carbohydrate Metabolism click chemistry Economics glycoprotein receptor Glycoproteins - metabolism Graphene Graphite - chemistry Hep G2 Cells Humans Microscopy, Fluorescence - methods Molecular Probe Techniques Nanocomposites Nanomaterials Nanoparticles - chemistry Nanostructure Oxides Receptors Receptors, Cell Surface - metabolism Recognition rhodamine Rhodamines - chemistry sugar
Title	Fluorogenic Probing of Specific Recognitions between Sugar Ligands and Glycoprotein Receptors on Cancer Cells by an Economic Graphene Nanocomposite
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