Rhodium‐Catalyzed Asymmetric Hydrogenation of All‐Carbon Aromatic Rings

• Published in: Angewandte Chemie International Edition Vol. 61; no. 34; pp. e202205623 - n/a
• Main Authors: Ding, Yi‐Xuan, Zhu, Zhou‐Hao, Chen, Mu‐Wang, Yu, Chang‐Bin, Zhou, Yong‐Gui
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 22.08.2022; Wiley Subscription Services, Inc
• Edition: International ed. in English
• Subjects: All-Carbon Aromatic Rings; Aromatic compounds; Aromaticity; Asymmetric Hydrogenation; Asymmetry; Carbon; Chemistry; Chemistry, Multidisciplinary; Cyclic compounds; Desymmetrization; Enantiomers; Hydrogenation; Kinetic Resolution; Ligands; Phosphine; Phosphines; Physical Sciences; Rhodium; Science & Technology; Steric hindrance; COMPLEX; Desymmetrization; ENANTIOSELECTIVE REDUCTION; QUINOLINES; Asymmetric Hydrogenation; RUTHENIUM; HETEROAROMATIC-COMPOUNDS; All-Carbon Aromatic Rings; PHOSPHORUS LIGANDS; KETONES; Kinetic Resolution; Rhodium; ACCESS

Compared with heteroarenes, homogeneous asymmetric hydrogenation of all‐carbon aromatic rings is a longstanding challenge in organic synthesis due to the strong aromaticity and difficult enantioselective control. Herein, we report the rhodium/diphosphine‐catalyzed asymmetric hydrogenation of all‐car...