Blood Pressure and Risks of Cognitive Impairment and Dementia: A Systematic Review and Meta-Analysis of 209 Prospective Studies

• Published in: Hypertension (Dallas, Tex. 1979) Vol. 76; no. 1; pp. 217 - 225
• Main Authors: Ou, Ya-Nan, Tan, Chen-Chen, Shen, Xue-Ning, Xu, Wei, Hou, Xiao-He, Dong, Qiang, Tan, Lan, Yu, Jin-Tai
• Format: Journal Article
• Language: English
• Published: United States American Heart Association, Inc 01.07.2020
• Subjects: Adult; Age Factors; Aged; Alzheimer Disease - epidemiology; Antihypertensive Agents - therapeutic use; Blood Pressure; Causality; Cognition Disorders - epidemiology; Comorbidity; Dementia - epidemiology; Follow-Up Studies; Humans; Hypertension - drug therapy; Hypertension - epidemiology; Hypotension, Orthostatic - epidemiology; Least-Squares Analysis; Middle Aged; Prospective Studies; Risk; meta-analysis; blood pressure; dementia; Alzheimer disease; hypertension

Controversies persist regarding the association between blood pressure (BP) and the risks of cognitive impairment and dementia due to inconsistent definitions of BP exposure and varying population characteristics. Here, we searched PubMed and performed a meta-analysis of the influence of BP exposure...