High-throughput nucleoside phosphate monitoring in mammalian cell fed-batch cultivation using quantitative matrix-assisted laser desorption/ionization time-of-flight mass spectrometry - Steinhoff, Robert F; Ivarsson, Marija; Habicher, Tobias; Villiger, Thomas K; Boertz, Jens; Krismer, Jasmin; Fagerer, Stephan R; Soos, Miroslav; Morbidelli, Massimo; Pabst, Martin; Zenobi, Renato (Biotechnology journal, 2015)
Keywords: Adenosine Triphosphate - metabolism; Animals; Cell Culture Techniques - methods; Cell Line; Cell Survival; Intracellular Space - metabolism; Metabolomics - methods; Mice; Principal Component Analysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods; Microarrays for mass spectrometry (MAMS); Automated sample aliquoting; MALDI-MS; Monoclonal antibody production; ATP