Hepatitis B virus reactivation among hepatitis C patients treated with direct-acting antiviral therapies in routine clinical practice

• Published in: Journal of clinical virology Vol. 93; pp. 66 - 70
• Main Authors: Loggi, Elisabetta, Gitto, Stefano, Galli, Silvia, Minichiello, Mario, Conti, Fabio, Grandini, Elena, Scuteri, Alessandra, Vitale, Giovanni, Di Donato, Roberto, Cursaro, Carmela, Furlini, Giuliano, Andreone, Pietro
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.08.2017
• Subjects: Aged; Aged, 80 and over; Allergy and Immunology; Antiviral Agents - adverse effects; Antiviral Agents - therapeutic use; Co-infection; Coinfection - drug therapy; Coinfection - virology; Direct-acting antiviral; DNA, Viral - blood; Female; Hepatitis B; Hepatitis B - blood; Hepatitis B - immunology; Hepatitis B - virology; Hepatitis B Antibodies - blood; Hepatitis B Surface Antigens - blood; Hepatitis B virus - physiology; Hepatitis C; Hepatitis C - blood; Hepatitis C - drug therapy; Hepatitis C - virology; Humans; Infectious Disease; Male; Middle Aged; Reactivation; Retrospective Studies; Virus Activation - drug effects; Reactivation; Co-infection; Hepatitis C; Direct-acting antiviral; Hepatitis B; Direct-acting Antiviral

•Past HBV infection seems not to predispose to HBV reactivation during DAA.•HBsAg-positive subjects should be controlled during and after DAA treatment.•Screening for HBV and longitudinal monitoring in selected cases are mandatory. Hepatitis B (HBV) reactivation in chronic hepatitis C (CHC) patients...