end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos

• Published in: Genes & development Vol. 11; no. 21; pp. 2883 - 2896
• Main Authors: Zhu, J, Hill, R J, Heid, P J, Fukuyama, M, Sugimoto, A, Priess, J R, Rothman, J H
• Format: Journal Article
• Language: English
• Published: United States Cold Spring Harbor Laboratory Press 01.11.1997
• Subjects: Amino Acid Sequence; Animals; Base Sequence; Caenorhabditis elegans - embryology; Caenorhabditis elegans - genetics; Caenorhabditis elegans Proteins; Cell Division; Chickens; Codon; Consensus Sequence; Conserved Sequence; Drosophila; Embryo, Nonmammalian - cytology; Embryo, Nonmammalian - physiology; Endoderm - physiology; Female; GATA Transcription Factors; Genes, Helminth; Genomic Imprinting; Helminth Proteins - biosynthesis; Helminth Proteins - chemistry; Homozygote; Molecular Sequence Data; Research Paper; Sequence Alignment; Sequence Homology, Amino Acid; Transcription Factors - biosynthesis; Transcription Factors - chemistry; Transcription Factors - genetics; Xenopus; Zinc Fingers

The endoderm in the nematode Caenorhabditis elegans is clonally derived from the E founder cell. We identified a single genomic region (the endoderm-determining region, or EDR) that is required for the production of the entire C. elegans endoderm. In embryos lacking the EDR, the E cell gives rise to...