Identifying Actionable Variants Using Capture-Based Targeted Sequencing in 563 Patients With Non-Small Cell Lung Carcinoma

• Published in: Frontiers in oncology Vol. 11; p. 812433
• Main Authors: Jiang, Haiping, Wang, Yinan, Xu, Hanlin, Lei, Wei, Yu, Xiaoyun, Tian, Haiying, Meng, Cong, Wang, Xueying, Zhao, Zicheng, Jin, Xiangfeng
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 04.02.2022
• Subjects: capture-based targeted sequencing; EGFR; mutation; NSCLC; Oncology; targeted therapy; capture-based targeted sequencing; mutation; targeted therapy; NSCLC; EGFR

Although the NSCLC diagnostic standards recommend the detection of driver gene mutation, comprehensive genomic profiling has not been used widely in clinical practice. As to the different mutation spectrum characteristics between populations, the research based on Chinese NSCLC cohort is very import...