Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects

Tests that allow the precise determination of psychophysical thresholds for vibration and grating orientation provide valuable information about mechanosensory function that are relevant for clinical diagnosis as well as for basic research. Here, we describe two psychophysical tests designed to dete...

Full description

Saved in:
Bibliographic Details
Published inJournal of visualized experiments no. 115
Main Authors Moshourab, Rabih, Frenzel, Henning, Lechner, Stefan, Haseleu, Julia, Bégay, Valérie, Omerbašić, Damir, Lewin, Gary R.
Format Journal Article
LanguageEnglish
Published United States MyJove Corporation 01.09.2016
Subjects
automation
Behavior
deafness
detection limit
Fingers - physiology
Humans
Orientation - physiology
Physical Stimulation - instrumentation
Physical Stimulation - methods
Sensory Thresholds - physiology
Touch - physiology
twins
Vibration
Online AccessGet full text

Cover

Abstract Tests that allow the precise determination of psychophysical thresholds for vibration and grating orientation provide valuable information about mechanosensory function that are relevant for clinical diagnosis as well as for basic research. Here, we describe two psychophysical tests designed to determine the vibration detection threshold (automated system) and tactile spatial acuity (handheld device). Both procedures implement a two-interval forced-choice and a transformed-rule up and down experimental paradigm. These tests have been used to obtain mechanosensory profiles for individuals from distinct human cohorts such as twins or people with sensorineural deafness.
AbstractList Tests that allow the precise determination of psychophysical thresholds for vibration and grating orientation provide valuable information about mechanosensory function that are relevant for clinical diagnosis as well as for basic research. Here, we describe two psychophysical tests designed to determine the vibration detection threshold (automated system) and tactile spatial acuity (handheld device). Both procedures implement a two-interval forced-choice and a transformed-rule up and down experimental paradigm. These tests have been used to obtain mechanosensory profiles for individuals from distinct human cohorts such as twins or people with sensorineural deafness.
Tests that allow the precise determination of psychophysical thresholds for vibration and grating orientation provide valuable information about mechanosensory function that are relevant for clinical diagnosis as well as for basic research. Here, we describe two psychophysical tests designed to determine the vibration detection threshold (automated system) and tactile spatial acuity (handheld device). Both procedures implement a two-interval forced-choice and a transformed-rule up and down experimental paradigm. These tests have been used to obtain mechanosensory profiles for individuals from distinct human cohorts such as twins or people with sensorineural deafness.Tests that allow the precise determination of psychophysical thresholds for vibration and grating orientation provide valuable information about mechanosensory function that are relevant for clinical diagnosis as well as for basic research. Here, we describe two psychophysical tests designed to determine the vibration detection threshold (automated system) and tactile spatial acuity (handheld device). Both procedures implement a two-interval forced-choice and a transformed-rule up and down experimental paradigm. These tests have been used to obtain mechanosensory profiles for individuals from distinct human cohorts such as twins or people with sensorineural deafness.
Author Bégay, Valérie
Lechner, Stefan
Lewin, Gary R.
Moshourab, Rabih
Omerbašić, Damir
Frenzel, Henning
Haseleu, Julia
AuthorAffiliation 1 Department of Anesthesiology and Intensive Care Medicine, Charite Universitätsmedzin, Campus Virchow Klinikum und Campus Charite Mitte
3 Institute of Pharmacology, University of Heidelberg
2 Department of Neuroscience, Molecular Physiology of Somatic Sensation, Max Delbrück Center for Molecular Medicine
AuthorAffiliation_xml – name: 3 Institute of Pharmacology, University of Heidelberg
– name: 2 Department of Neuroscience, Molecular Physiology of Somatic Sensation, Max Delbrück Center for Molecular Medicine
– name: 1 Department of Anesthesiology and Intensive Care Medicine, Charite Universitätsmedzin, Campus Virchow Klinikum und Campus Charite Mitte
Author_xml – sequence: 1
  givenname: Rabih
  surname: Moshourab
  fullname: Moshourab, Rabih
– sequence: 2
  givenname: Henning
  surname: Frenzel
  fullname: Frenzel, Henning
– sequence: 3
  givenname: Stefan
  surname: Lechner
  fullname: Lechner, Stefan
– sequence: 4
  givenname: Julia
  surname: Haseleu
  fullname: Haseleu, Julia
– sequence: 5
  givenname: Valérie
  surname: Bégay
  fullname: Bégay, Valérie
– sequence: 6
  givenname: Damir
  surname: Omerbašić
  fullname: Omerbašić, Damir
– sequence: 7
  givenname: Gary R.
  surname: Lewin
  fullname: Lewin, Gary R.
BackLink https://www.ncbi.nlm.nih.gov/pubmed/27684317$$D View this record in MEDLINE/PubMed
BookMark eNqFkUtLAzEUhYMoVmv_gmQjCFJNMq9kI4hvUFy0iq5CJr1jIzNJTWYE_72x1lK7cXXvTb4czs3ZRZvWWUBoQMlxUgh6kjGR5xtoh4qUDAkvnjdX-h7aDeGNkJyRjG-jHitynia02EEv96BC56EB22JX4SdTetUaZ_EFtKDn3XjqIUxdPcHKTvBYxdMa8GgWOVXjM92Z9hMbi2-6Rlk86sq3-DDsoa1K1QEGi9pHj1eX4_Ob4d3D9e352d1QpzRrh7rUBFIioEooS7RIS84V4TSlFdCcUCJIobKsBCCa0xxYKeKsJoykTDEFSR-d_ujOurKBiY6LeFXLmTeN8p_SKSP_3lgzla_uQ2ZEUMFZFDhcCHj33kFoZWOChrpWFlwXJGNZwijPmfgXpZxljOaC8Yjur9pa-vn9-ggc_ADauxA8VEuEEvkdqZxHGrmjNU6bdh5R3MbUa_QXNkWhKw
CitedBy_id crossref_primary_10_1016_j_knee_2018_10_014
crossref_primary_10_3389_fnins_2021_682113
crossref_primary_10_1038_s41598_017_04074_0
ContentType Journal Article
Copyright Copyright © 2016, Journal of Visualized Experiments 2016
Copyright_xml – notice: Copyright © 2016, Journal of Visualized Experiments 2016
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
7S9
L.6
5PM
DOI 10.3791/52966
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
AGRICOLA
AGRICOLA - Academic
PubMed Central (Full Participant titles)
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
AGRICOLA
AGRICOLA - Academic
DatabaseTitleList
MEDLINE
AGRICOLA
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 1940-087X
ExternalDocumentID PMC5091982
27684317
10_3791_52966
Genre Video-Audio Media
Journal Article
GrantInformation_xml – fundername: European Research Council
  grantid: 294678
GroupedDBID ---
223
29L
53G
5GY
AAHBH
AAHTB
AAYXX
ABPEJ
ACGFO
ADBBV
AKRSQ
ALMA_UNASSIGNED_HOLDINGS
AOIJS
BAWUL
CITATION
CS3
DIK
E3Z
GX1
HYE
OK1
RPM
SJN
CGR
CUY
CVF
ECM
EIF
NPM
7X8
7S9
L.6
5PM
ID FETCH-LOGICAL-c415t-cbc0e409ef3123c94b88a08141fe16010907a55bee0c816e2b97a5ad2042a2ae3
ISSN 1940-087X
IngestDate Thu Aug 21 18:30:02 EDT 2025
Fri Jul 11 05:28:04 EDT 2025
Fri Jul 11 09:01:12 EDT 2025
Sat May 31 02:10:06 EDT 2025
Thu Apr 24 22:59:55 EDT 2025
Tue Jul 01 05:19:57 EDT 2025
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 115
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c415t-cbc0e409ef3123c94b88a08141fe16010907a55bee0c816e2b97a5ad2042a2ae3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Undefined-3
Correspondence to: Rabih Moshourab at rabih.moshourab@mdc-berlin.de
OpenAccessLink https://www.ncbi.nlm.nih.gov/pmc/articles/5091982
PMID 27684317
PQID 1825216928
PQPubID 23479
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_5091982
proquest_miscellaneous_2253218629
proquest_miscellaneous_1825216928
pubmed_primary_27684317
crossref_primary_10_3791_52966
crossref_citationtrail_10_3791_52966
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2016-09-01
PublicationDateYYYYMMDD 2016-09-01
PublicationDate_xml – month: 09
  year: 2016
  text: 2016-09-01
  day: 01
PublicationDecade 2010
PublicationPlace United States
PublicationPlace_xml – name: United States
PublicationTitle Journal of visualized experiments
PublicationTitleAlternate J Vis Exp
PublicationYear 2016
Publisher MyJove Corporation
Publisher_xml – name: MyJove Corporation
SSID ssj0062058
Score 2.1149447
Snippet Tests that allow the precise determination of psychophysical thresholds for vibration and grating orientation provide valuable information about mechanosensory...
SourceID pubmedcentral
proquest
pubmed
crossref
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
SubjectTerms automation
Behavior
deafness
detection limit
Fingers - physiology
Humans
Orientation - physiology
Physical Stimulation - instrumentation
Physical Stimulation - methods
Sensory Thresholds - physiology
Touch - physiology
twins
Vibration
Title Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects
URI https://www.ncbi.nlm.nih.gov/pubmed/27684317
https://www.proquest.com/docview/1825216928
https://www.proquest.com/docview/2253218629
https://pubmed.ncbi.nlm.nih.gov/PMC5091982
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1dq9MwGA56RBFE_HZ-HCKc2-qatml6KephCPNCd2RelSR7iwPpZGsF9-t936RNt7mDHzdly5Km9HmWPEneD8bOCmUyyKyOjLZJlCopI51KG2WJtjZHwZHn5I08_SAnF-n7eTYfXAicd0ljXtrtUb-S_0EVyxBX8pL9B2TDTbEAPyO-eEWE8fpXGE-HDT4SfZ9p6evwfAsN-BzgM8RqQ0dM7pRgRm4MZD1IdtQEjm1JhVO8K7eZj8MI7ctsLpGsP5Yb8sHcokgdMgMEUT5dYUftWrsTno_aLMNO8_ka6q03B5iAy5E02AHZ3uXmUwPVQNWJpjRQbe_CrXd3J2IZzK_6AbUg81GVz_18c6Ss45d36jwc0JO8oAGdDoePBMw-mMiCeSEubKhh6ZpdZdcELiFEv5PjZ2kpxi53a3iWG-xW198r12xfp_y2-Di0od0RJbM77HYHDX_tqXGXXYH6Hrvu84v-vM--7BCEryoeCMIDQXggCEeC8I4gvCMI9wThy5o7gvCeIA_Yxfm72ZtJ1OXSiCxKtCayxo4B1_JQJahVbJEapTTKwTSuIJbOPDfXWWYAxlbFEoQp8LteCBzUtdCQPGQn9aqGx4xXME4KnZnMLCj6nVJSacgrrUySLXIRj9hZ_-ZK2wWap3wn38o9XEbsNFT77iOrHFZ40b_2Esc8OsjSNazaTYlrYlSdshDq8jo4TyWUb00UI_bIQxW6EXT6jMJ5xPI9EEMFirm-_0u9_Opir5O-LpR48qeHf8puDn-HZ-ykWbfwHOVrY04dD38BoJmgSQ
linkProvider National Library of Medicine
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Measurement+of+Vibration+Detection+Threshold+and+Tactile+Spatial+Acuity+in+Human+Subjects&rft.jtitle=Journal+of+visualized+experiments&rft.au=Moshourab%2C+Rabih&rft.au=Frenzel%2C+Henning&rft.au=Lechner%2C+Stefan&rft.au=Haseleu%2C+Julia&rft.date=2016-09-01&rft.issn=1940-087X&rft.eissn=1940-087X&rft.issue=115&rft_id=info:doi/10.3791%2F52966&rft.externalDBID=n%2Fa&rft.externalDocID=10_3791_52966
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1940-087X&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1940-087X&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1940-087X&client=summon