Invasion and metastasis in cancer: molecular insights and therapeutic targets

• Published in: Signal transduction and targeted therapy Vol. 10; no. 1; pp. 57 - 38
• Main Authors: Li, Yongxing, Liu, Fengshuo, Cai, Qingjin, Deng, Lijun, Ouyang, Qin, Zhang, Xiang H.-F., Zheng, Ji
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 21.02.2025; Nature Publishing Group
• Subjects: 631/67/1059; 631/67/322; 692/4028/67; Animals; Biomedical Research; Bone tumors; Brain tumors; Cancer; Cancer Research; Cell Biology; Humans; Internal Medicine; Medical prognosis; Medicine; Medicine & Public Health; Metastases; Metastasis; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms - drug therapy; Neoplasms - genetics; Neoplasms - metabolism; Neoplasms - pathology; Oncology; Pathology; Quality of life; Review Article; Therapeutic applications; Therapeutic targets; Tropism; Tumors

The progression of malignant tumors leads to the development of secondary tumors in various organs, including bones, the brain, liver, and lungs. This metastatic process severely impacts the prognosis of patients, significantly affecting their quality of life and survival rates. Research efforts hav...