Factors influencing the success of anterior cruciate ligament repair with dynamic intraligamentary stabilisation
Purpose Primary repair of the anterior cruciate ligament (ACL) has regained interest of clinicians with recent development of novel repair techniques. Dynamic intraligamentary stabilisation was introduced in an attempt to promote healing by shielding cyclic loads acting upon the ACL during the heali...
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Published in | Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA Vol. 25; no. 12; pp. 3923 - 3928 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Berlin/Heidelberg
Springer Berlin Heidelberg
01.12.2017
Springer Nature B.V |
Subjects | |
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Abstract | Purpose
Primary repair of the anterior cruciate ligament (ACL) has regained interest of clinicians with recent development of novel repair techniques. Dynamic intraligamentary stabilisation was introduced in an attempt to promote healing by shielding cyclic loads acting upon the ACL during the healing phase. The aim of this study was to identify negative factors likely to influence success of this procedure.
Methods
Between 2009 and 2014, 264 patients with an acute ACL rupture undergoing dynamic intraligamentary stabilisation were included in this study. Patients were evaluated for anterior/posterior laxity; range of motion and patient reported outcome measures. Adverse events and re-operations were noted. Failure was defined as AP Translation >3 mm, re-rupture or conversion to ACL reconstruction. Minimum follow-up was 24 months. Univariate and multivariate regression models were utilized to determine predictors of failure.
Results
An overall complication rate of 15.1% was noted comprising 9.5% (
n
= 25) re-ruptures, 4.1% (
n
= 11) persistent instability, and 1.5% (
n
= 4) > 10° fixed flexion deformity. Two factors were identified as negative predictors of failure: (1) pursuit of competitive sport activities with a Tegner pre-injury score >7 (Odds Ratio (OR) 4.4, CI 1.2–15.9,
p
= 0.02) and (2) mid-substance ACL rupture location (OR 2.5, 1.1–5.7,
p
= 0.02). When neither of those risk factors occurred the failure rate was limited to 3.9%.
Conclusions
Correct patient selection and narrowing of indications are necessary to maintain high success rates of the procedure. Mid-substance ACL ruptures and a high pre-injury sports activity level are two predictors of inferior outcome.
Level of evidence
II. |
---|---|
AbstractList | PurposePrimary repair of the anterior cruciate ligament (ACL) has regained interest of clinicians with recent development of novel repair techniques. Dynamic intraligamentary stabilisation was introduced in an attempt to promote healing by shielding cyclic loads acting upon the ACL during the healing phase. The aim of this study was to identify negative factors likely to influence success of this procedure.MethodsBetween 2009 and 2014, 264 patients with an acute ACL rupture undergoing dynamic intraligamentary stabilisation were included in this study. Patients were evaluated for anterior/posterior laxity; range of motion and patient reported outcome measures. Adverse events and re-operations were noted. Failure was defined as AP Translation >3 mm, re-rupture or conversion to ACL reconstruction. Minimum follow-up was 24 months. Univariate and multivariate regression models were utilized to determine predictors of failure.ResultsAn overall complication rate of 15.1% was noted comprising 9.5% (n = 25) re-ruptures, 4.1% (n = 11) persistent instability, and 1.5% (n = 4) > 10° fixed flexion deformity. Two factors were identified as negative predictors of failure: (1) pursuit of competitive sport activities with a Tegner pre-injury score >7 (Odds Ratio (OR) 4.4, CI 1.2–15.9, p = 0.02)and (2) mid-substance ACL rupture location (OR 2.5, 1.1–5.7, p = 0.02). When neither of those risk factors occurred the failure rate was limited to 3.9%.ConclusionsCorrect patient selection and narrowing of indications are necessary to maintain high success rates of the procedure. Mid-substance ACL ruptures and a high pre-injury sports activity level are two predictors of inferior outcome.Level of evidence II. PURPOSEPrimary repair of the anterior cruciate ligament (ACL) has regained interest of clinicians with recent development of novel repair techniques. Dynamic intraligamentary stabilisation was introduced in an attempt to promote healing by shielding cyclic loads acting upon the ACL during the healing phase. The aim of this study was to identify negative factors likely to influence success of this procedure.METHODSBetween 2009 and 2014, 264 patients with an acute ACL rupture undergoing dynamic intraligamentary stabilisation were included in this study. Patients were evaluated for anterior/posterior laxity; range of motion and patient reported outcome measures. Adverse events and re-operations were noted. Failure was defined as AP Translation >3 mm, re-rupture or conversion to ACL reconstruction. Minimum follow-up was 24 months. Univariate and multivariate regression models were utilized to determine predictors of failure.RESULTSAn overall complication rate of 15.1% was noted comprising 9.5% (n = 25) re-ruptures, 4.1% (n = 11) persistent instability, and 1.5% (n = 4) > 10° fixed flexion deformity. Two factors were identified as negative predictors of failure: (1) pursuit of competitive sport activities with a Tegner pre-injury score >7 (Odds Ratio (OR) 4.4, CI 1.2-15.9, p = 0.02) and (2) mid-substance ACL rupture location (OR 2.5, 1.1-5.7, p = 0.02). When neither of those risk factors occurred the failure rate was limited to 3.9%.CONCLUSIONSCorrect patient selection and narrowing of indications are necessary to maintain high success rates of the procedure. Mid-substance ACL ruptures and a high pre-injury sports activity level are two predictors of inferior outcome.LEVEL OF EVIDENCEII. Purpose Primary repair of the anterior cruciate ligament (ACL) has regained interest of clinicians with recent development of novel repair techniques. Dynamic intraligamentary stabilisation was introduced in an attempt to promote healing by shielding cyclic loads acting upon the ACL during the healing phase. The aim of this study was to identify negative factors likely to influence success of this procedure. Methods Between 2009 and 2014, 264 patients with an acute ACL rupture undergoing dynamic intraligamentary stabilisation were included in this study. Patients were evaluated for anterior/posterior laxity; range of motion and patient reported outcome measures. Adverse events and re-operations were noted. Failure was defined as AP Translation >3 mm, re-rupture or conversion to ACL reconstruction. Minimum follow-up was 24 months. Univariate and multivariate regression models were utilized to determine predictors of failure. Results An overall complication rate of 15.1% was noted comprising 9.5% ( n = 25) re-ruptures, 4.1% ( n = 11) persistent instability, and 1.5% ( n = 4) > 10° fixed flexion deformity. Two factors were identified as negative predictors of failure: (1) pursuit of competitive sport activities with a Tegner pre-injury score >7 (Odds Ratio (OR) 4.4, CI 1.2–15.9, p = 0.02) and (2) mid-substance ACL rupture location (OR 2.5, 1.1–5.7, p = 0.02). When neither of those risk factors occurred the failure rate was limited to 3.9%. Conclusions Correct patient selection and narrowing of indications are necessary to maintain high success rates of the procedure. Mid-substance ACL ruptures and a high pre-injury sports activity level are two predictors of inferior outcome. Level of evidence II. Primary repair of the anterior cruciate ligament (ACL) has regained interest of clinicians with recent development of novel repair techniques. Dynamic intraligamentary stabilisation was introduced in an attempt to promote healing by shielding cyclic loads acting upon the ACL during the healing phase. The aim of this study was to identify negative factors likely to influence success of this procedure. Between 2009 and 2014, 264 patients with an acute ACL rupture undergoing dynamic intraligamentary stabilisation were included in this study. Patients were evaluated for anterior/posterior laxity; range of motion and patient reported outcome measures. Adverse events and re-operations were noted. Failure was defined as AP Translation >3 mm, re-rupture or conversion to ACL reconstruction. Minimum follow-up was 24 months. Univariate and multivariate regression models were utilized to determine predictors of failure. An overall complication rate of 15.1% was noted comprising 9.5% (n = 25) re-ruptures, 4.1% (n = 11) persistent instability, and 1.5% (n = 4) > 10° fixed flexion deformity. Two factors were identified as negative predictors of failure: (1) pursuit of competitive sport activities with a Tegner pre-injury score >7 (Odds Ratio (OR) 4.4, CI 1.2-15.9, p = 0.02) and (2) mid-substance ACL rupture location (OR 2.5, 1.1-5.7, p = 0.02). When neither of those risk factors occurred the failure rate was limited to 3.9%. Correct patient selection and narrowing of indications are necessary to maintain high success rates of the procedure. Mid-substance ACL ruptures and a high pre-injury sports activity level are two predictors of inferior outcome. II. |
Author | Krismer, Anna M. Kohlhof, Hendrik Ahmad, Sufian S. Gousopoulos, Lampros Ateschrang, Atesch Kohl, Sandro |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28210790$$D View this record in MEDLINE/PubMed |
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Copyright | European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2017 Knee Surgery, Sports Traumatology, Arthroscopy is a copyright of Springer, (2017). All Rights Reserved. |
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Keywords | Predictive factors Anterior cruciate ligament (ACL) Rerupture Dynamic intraligamentary stabilisation (DIS) |
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Defining a rationale for augmentation publication-title: Am J Sports Med doi: 10.1177/036354659101900307 contributor: fullname: Reiter – volume: 23 start-page: 636 issue: 3 year: 2015 end-page: 639 ident: CR3 article-title: Anatomic ACL reconstruction: the final answer? publication-title: Knee Surg Sports Traumatol Arthrosc doi: 10.1007/s00167-014-3323-8 contributor: fullname: Clancy – volume: 43 start-page: 121 issue: 1 year: 2015 end-page: 127 ident: CR1 article-title: Patient predictors of early revision surgery after anterior cruciate ligament reconstruction a cohort study of 16,930 patients with 2-year follow-up publication-title: Am J Sports Med doi: 10.1177/0363546514552788 contributor: fullname: Samuelsson – volume: 98-B start-page: 793 issue: 6 year: 2016 end-page: 798 ident: CR8 article-title: Dynamic intraligamentary stabilisation: initial experience with treatment of acute ACL ruptures publication-title: Bone Joint doi: 10.1302/0301-620X.98B6.35040 contributor: fullname: Ahmad – volume: 23 start-page: 549 issue: 3 year: 2016 end-page: 553 ident: CR2 article-title: Functional recovery following primary ACL repair with dynamic intraligamentary stabilization publication-title: Knee doi: 10.1016/j.knee.2016.01.012 contributor: fullname: Kohl – volume: 29 start-page: 1566 issue: 9 year: 2013 end-page: 1571 ident: CR4 article-title: Long-term failure of anterior cruciate ligament reconstruction publication-title: Arthroscopy doi: 10.1016/j.arthro.2013.04.014 contributor: fullname: Lubowitz – volume: 43 start-page: 1583 issue: 7 year: 2015 end-page: 1590 ident: CR7 article-title: Risk factors and predictors of subsequent ACL injury in either knee after ACL reconstruction: prospective analysis of 2488 primary ACL reconstructions from the MOON cohort publication-title: Am J Sports Med doi: 10.1177/0363546515578836 contributor: fullname: Spindler – volume: 21 start-page: 948 issue: 8 year: 2005 end-page: 957 ident: CR11 article-title: Incidence and risk factors for graft rupture and contralateral rupture after anterior cruciate ligament reconstruction publication-title: Arthroscopy doi: 10.1016/j.arthro.2005.04.110 contributor: fullname: Refshauge – volume: 98-B start-page: 793 issue: 6 year: 2016 ident: 4445_CR8 publication-title: Bone Joint doi: 10.1302/0301-620X.98B6.35040 contributor: fullname: S Kohl – volume: 43 start-page: 2164 issue: 9 year: 2015 ident: 4445_CR13 publication-title: Am J Sports Med doi: 10.1177/0363546515591263 contributor: fullname: S Thompson – volume: 43 start-page: 1583 issue: 7 year: 2015 ident: 4445_CR7 publication-title: Am J Sports Med doi: 10.1177/0363546515578836 contributor: fullname: CC Kaeding – volume: 23 start-page: 549 issue: 3 year: 2016 ident: 4445_CR2 publication-title: Knee doi: 10.1016/j.knee.2016.01.012 contributor: fullname: L Büchler – volume: 19 start-page: 243 issue: 3 year: 1991 ident: 4445_CR12 publication-title: Am J Sports Med doi: 10.1177/036354659101900307 contributor: fullname: MF Sherman – volume: 23 start-page: 636 issue: 3 year: 2015 ident: 4445_CR3 publication-title: Knee Surg Sports Traumatol Arthrosc doi: 10.1007/s00167-014-3323-8 contributor: fullname: WG Clancy – volume: 43 start-page: 121 issue: 1 year: 2015 ident: 4445_CR1 publication-title: Am J Sports Med doi: 10.1177/0363546514552788 contributor: fullname: D Andernord – volume: 21 start-page: 948 issue: 8 year: 2005 ident: 4445_CR11 publication-title: Arthroscopy doi: 10.1016/j.arthro.2005.04.110 contributor: fullname: L Salmon – volume: 29 start-page: 1566 issue: 9 year: 2013 ident: 4445_CR4 publication-title: Arthroscopy doi: 10.1016/j.arthro.2013.04.014 contributor: fullname: SN Crawford – year: 2015 ident: 4445_CR6 publication-title: Knee Surg Sports Traumatol Arthrosc doi: 10.1007/s00167-015-3838-7 contributor: fullname: DS Evangelopoulos – volume: 23 start-page: 1215 issue: 4 year: 2015 ident: 4445_CR5 publication-title: Knee Surg Sports Traumatol Arthrosc doi: 10.1007/s00167-014-2949-x contributor: fullname: S Eggli – volume: 35 start-page: 1756 issue: 10 year: 2007 ident: 4445_CR9 publication-title: Am J Sports Med doi: 10.1177/0363546507307396 contributor: fullname: LS Lohmander – volume: 31 start-page: 990 issue: 5 year: 2015 ident: 4445_CR10 publication-title: Arthroscopy doi: 10.1016/j.arthro.2014.11.016 contributor: fullname: BL Proffen |
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SubjectTerms | Adolescent Adult Anterior cruciate ligament Anterior Cruciate Ligament Injuries - surgery Anterior Cruciate Ligament Reconstruction - methods Child Cyclic loads Deformation Failure Female Healing Humans Joint Instability - prevention & control Knee Male Medicine Medicine & Public Health Orthopedics Patients Range of Motion, Articular Regression analysis Regression models Reoperation Repair Risk analysis Risk factors Rupture Rupture - surgery Rupturing Shielding Stability Success Treatment Outcome Young Adult |
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Title | Factors influencing the success of anterior cruciate ligament repair with dynamic intraligamentary stabilisation |
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