Long-term Follow-up on NRG Oncology RTOG 0915 (NCCTG N0927): A Randomized Phase 2 Study Comparing 2 Stereotactic Body Radiation Therapy Schedules for Medically Inoperable Patients With Stage I Peripheral Non-Small Cell Lung Cancer

• Published in: International journal of radiation oncology, biology, physics Vol. 103; no. 5; pp. 1077 - 1084
• Main Authors: Videtic, Gregory M., Paulus, Rebecca, Singh, Anurag K., Chang, Joe Y., Parker, William, Olivier, Kenneth R., Timmerman, Robert D., Komaki, Ritsuko R., Urbanic, James J., Stephans, Kevin L., Yom, Sue S., Robinson, Clifford G., Belani, Chandra P., Iyengar, Puneeth, Ajlouni, Munther I., Gopaul, Darindra D., Gomez Suescun, Jorge B., McGarry, Ronald C., Choy, Hak, Bradley, Jeffrey D.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2019
• Subjects: Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung - mortality; Carcinoma, Non-Small-Cell Lung - pathology; Carcinoma, Non-Small-Cell Lung - radiotherapy; Confidence Intervals; Dose Fractionation, Radiation; Female; Follow-Up Studies; Humans; Lung Neoplasms - mortality; Lung Neoplasms - pathology; Lung Neoplasms - radiotherapy; Male; Middle Aged; Progression-Free Survival; Radiation Injuries - pathology; Radiosurgery - adverse effects; Radiosurgery - methods; Radiosurgery - mortality; Time Factors; Treatment Failure

To present long-term results of RTOG 0915/NCCTG N0927, a randomized lung stereotactic body radiation therapy trial of 34 Gy in 1 fraction versus 48 Gy in 4 fractions. This was a phase 2 multicenter study of patients with medically inoperable non-small cell lung cancer with biopsy-proven peripheral T...