Alteration of lens and retina textures from mice embryos with folic acid deficiency: image processing analysis

• Published in: Graefe's archive for clinical and experimental ophthalmology Vol. 257; no. 1; pp. 111 - 123
• Main Authors: Sijilmassi, Ouafa, López-Alonso, José Manuel, Barrio Asensio, María Del Carmen, Del Río Sevilla, Aurora
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.01.2019; Springer Nature B.V
• Subjects: Basic Science; Collagen; Collagen (type IV); Deoxyribonucleic acid; DNA; DNA biosynthesis; Embryogenesis; Eye lens; Folic acid; Fourier analysis; Grain size; Image processing; Immunohistochemistry; Laminin; Medicine; Medicine & Public Health; Ophthalmology; Protein biosynthesis; Retina; Ribonucleic acid; RNA; Segmentation; Transcription; Laminin-1; Folic acid deficiency; Retina; Matlab texture analysis; Lens; Type IV collagen

Purpose Folic acid (FA) is an essential vitamin for embryonic development. It plays particularly a critical role in RNA, DNA and protein synthesis. On the other hand, the collagen IV and laminin-1 are important proteins during embryonic development. This study was done to find if FA deficiency at a...