The association of depression and painful physical symptoms–a review of the European literature

Objective: The presence of painful physical symptoms may confound the diagnosis of major depressive disorder and may worsen patient prognosis. Epidemiological literature was reviewed to investigate the association between depression and painful physical symptoms. Method: MEDLINE and EMBASE database...

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Published inEuropean psychiatry Vol. 21; no. 6; pp. 379 - 388
Main Authors Garcia-Cebrian, A., Gandhi, P., Demyttenaere, K., Peveler, R.
Format Journal Article
LanguageEnglish
Published Paris Elsevier SAS 01.09.2006
Elsevier
Subjects
Adult and adolescent clinical studies
Biological and medical sciences
Comorbidity
Depression
Depressive Disorder, Major - epidemiology
Europe
Europe - epidemiology
Humans
Medical sciences
Mood disorders
Pain
Pain Measurement
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Review
Severity of Illness Index
Somatoform Disorders - diagnosis
Somatoform Disorders - epidemiology
Europe
Depression
Pain
Review
Europe
Mood disorder
Symptomatology
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Abstract Objective: The presence of painful physical symptoms may confound the diagnosis of major depressive disorder and may worsen patient prognosis. Epidemiological literature was reviewed to investigate the association between depression and painful physical symptoms. Method: MEDLINE and EMBASE database searches were conducted. Studies where a definable organic basis for pain was given were excluded. The search was unrestricted by language but limited to European studies and countries. After filters were applied, 70 eligible studies were reviewed. Results: The majority of studies reviewed showed an association between depression and painful physical symptoms. Over 40% of all studies examining the association between pain and depression were carried out in pain clinics in secondary care. Very few studies were conducted in psychiatric settings. Conclusion: The findings of this review suggest that painful physical symptoms may be an important part of the depressive syndrome. Although the relationship between depression and painful physical symptoms is not yet fully understood, findings suggest that diagnosis and treatment of depression should involve investigating and treating the full spectrum of symptoms (emotional and physical). Further research in psychiatric and generalist settings is needed to elucidate the relationship between depression and painful physical symptoms as experienced by patients and at the clinical level.
AbstractList OBJECTIVEThe presence of painful physical symptoms may confound the diagnosis of major depressive disorder and may worsen patient prognosis. Epidemiological literature was reviewed to investigate the association between depression and painful physical symptoms. METHODMEDLINE and EMBASE database searches were conducted. Studies where a definable organic basis for pain was given were excluded. The search was unrestricted by language but limited to European studies and countries. After filters were applied, 70 eligible studies were reviewed. RESULTSThe majority of studies reviewed showed an association between depression and painful physical symptoms. Over 40% of all studies examining the association between pain and depression were carried out in pain clinics in secondary care. Very few studies were conducted in psychiatric settings. CONCLUSIONThe findings of this review suggest that painful physical symptoms may be an important part of the depressive syndrome. Although the relationship between depression and painful physical symptoms is not yet fully understood, findings suggest that diagnosis and treatment of depression should involve investigating and treating the full spectrum of symptoms (emotional and physical). Further research in psychiatric and generalist settings is needed to elucidate the relationship between depression and painful physical symptoms as experienced by patients and at the clinical level.
Objective: The presence of painful physical symptoms may confound the diagnosis of major depressive disorder and may worsen patient prognosis. Epidemiological literature was reviewed to investigate the association between depression and painful physical symptoms. Method: MEDLINE and EMBASE database searches were conducted. Studies where a definable organic basis for pain was given were excluded. The search was unrestricted by language but limited to European studies and countries. After filters were applied, 70 eligible studies were reviewed. Results: The majority of studies reviewed showed an association between depression and painful physical symptoms. Over 40% of all studies examining the association between pain and depression were carried out in pain clinics in secondary care. Very few studies were conducted in psychiatric settings. Conclusion: The findings of this review suggest that painful physical symptoms may be an important part of the depressive syndrome. Although the relationship between depression and painful physical symptoms is not yet fully understood, findings suggest that diagnosis and treatment of depression should involve investigating and treating the full spectrum of symptoms (emotional and physical). Further research in psychiatric and generalist settings is needed to elucidate the relationship between depression and painful physical symptoms as experienced by patients and at the clinical level.
Abstract Objective: The presence of painful physical symptoms may confound the diagnosis of major depressive disorder and may worsen patient prognosis. Epidemiological literature was reviewed to investigate the association between depression and painful physical symptoms. Method: MEDLINE and EMBASE database searches were conducted. Studies where a definable organic basis for pain was given were excluded. The search was unrestricted by language but limited to European studies and countries. After filters were applied, 70 eligible studies were reviewed. Results: The majority of studies reviewed showed an association between depression and painful physical symptoms. Over 40% of all studies examining the association between pain and depression were carried out in pain clinics in secondary care. Very few studies were conducted in psychiatric settings. Conclusion: The findings of this review suggest that painful physical symptoms may be an important part of the depressive syndrome. Although the relationship between depression and painful physical symptoms is not yet fully understood, findings suggest that diagnosis and treatment of depression should involve investigating and treating the full spectrum of symptoms (emotional and physical). Further research in psychiatric and generalist settings is needed to elucidate the relationship between depression and painful physical symptoms as experienced by patients and at the clinical level.
The presence of painful physical symptoms may confound the diagnosis of major depressive disorder and may worsen patient prognosis. Epidemiological literature was reviewed to investigate the association between depression and painful physical symptoms. MEDLINE and EMBASE database searches were conducted. Studies where a definable organic basis for pain was given were excluded. The search was unrestricted by language but limited to European studies and countries. After filters were applied, 70 eligible studies were reviewed. The majority of studies reviewed showed an association between depression and painful physical symptoms. Over 40% of all studies examining the association between pain and depression were carried out in pain clinics in secondary care. Very few studies were conducted in psychiatric settings. The findings of this review suggest that painful physical symptoms may be an important part of the depressive syndrome. Although the relationship between depression and painful physical symptoms is not yet fully understood, findings suggest that diagnosis and treatment of depression should involve investigating and treating the full spectrum of symptoms (emotional and physical). Further research in psychiatric and generalist settings is needed to elucidate the relationship between depression and painful physical symptoms as experienced by patients and at the clinical level.
Author Gandhi, P.
Demyttenaere, K.
Peveler, R.
Garcia-Cebrian, A.
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  surname: Garcia-Cebrian
  fullname: Garcia-Cebrian, A.
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  organization: European Health Outcomes Research, Erl Wood Manor, Sunninghill Road, Windlesham, Surrey GU20 6PH, UK
– sequence: 2
  givenname: P.
  surname: Gandhi
  fullname: Gandhi, P.
  organization: UK Medical, Eli Lilly and Co., Basingstoke, UK
– sequence: 3
  givenname: K.
  surname: Demyttenaere
  fullname: Demyttenaere, K.
  organization: Department of Psychiatry, University Hospital Gasthuisberg, Belgium
– sequence: 4
  givenname: R.
  surname: Peveler
  fullname: Peveler, R.
  organization: Mental Health Group, University of Southampton, UK
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https://www.ncbi.nlm.nih.gov/pubmed/16797937$$D View this record in MEDLINE/PubMed
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Snippet Objective: The presence of painful physical symptoms may confound the diagnosis of major depressive disorder and may worsen patient prognosis. Epidemiological...
The presence of painful physical symptoms may confound the diagnosis of major depressive disorder and may worsen patient prognosis. Epidemiological literature...
Abstract Objective: The presence of painful physical symptoms may confound the diagnosis of major depressive disorder and may worsen patient prognosis....
OBJECTIVEThe presence of painful physical symptoms may confound the diagnosis of major depressive disorder and may worsen patient prognosis. Epidemiological...
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SubjectTerms Adult and adolescent clinical studies
Biological and medical sciences
Comorbidity
Depression
Depressive Disorder, Major - epidemiology
Europe
Europe - epidemiology
Humans
Medical sciences
Mood disorders
Pain
Pain Measurement
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Review
Severity of Illness Index
Somatoform Disorders - diagnosis
Somatoform Disorders - epidemiology
Title The association of depression and painful physical symptoms–a review of the European literature
URI https://dx.doi.org/10.1016/j.eurpsy.2005.12.003
https://www.ncbi.nlm.nih.gov/pubmed/16797937
https://search.proquest.com/docview/68867566
Volume 21
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