Peripheral Type I Interferon Receptor Correlated with Oxidative Stress in Chronic Hepatitis B Virus Infection

• Published in: Journal of interferon & cytokine research Vol. 33; no. 8; pp. 405 - 414
• Main Authors: Zhao, Jing, Fan, Yu-Chen, Sun, Feng-Kai, Zhao, Ze-Hua, Wang, Li-Yuan, Hu, Lei-Hua, Yin, Yan-Ping, Li, Tao, Gao, Shuai, Wang, Kai
• Format: Journal Article
• Language: English
• Published: United States Mary Ann Liebert, Inc 01.08.2013
• Subjects: Adult; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Gene Expression; Glutathione - blood; Glutathione Peroxidase - blood; Glutathione Transferase - blood; Hepatitis B, Chronic - blood; Hepatitis B, Chronic - genetics; Hepatitis B, Chronic - metabolism; Humans; Liver Cirrhosis - blood; Liver Cirrhosis - genetics; Liver Cirrhosis - metabolism; Lymphocytes - metabolism; Male; Malondialdehyde - blood; Middle Aged; Monocytes - metabolism; Oxidative Stress; Receptor, Interferon alpha-beta - blood; Receptor, Interferon alpha-beta - genetics; Receptor, Interferon alpha-beta - metabolism; Research Reports; Reverse Transcriptase Polymerase Chain Reaction; Xanthine Oxidase - blood

Type I interferon receptor (IFNAR) has been involved in the progression of chronic hepatitis B (CHB). Oxidative stress is also associated with hepatitis B virus (HBV) infection and might contribute to the structure and function of protein synthesis including the IFNAR family. This study was aimed to...