The bistable mitotic switch in fission yeast

• Published in: Molecular biology of the cell Vol. 35; no. 6; p. mbcE24030142
• Main Authors: Novák, Béla, Tyson, John J.
• Format: Journal Article
• Language: English
• Published: United States American Society for Cell Biology 01.06.2024; The American Society for Cell Biology
• Subjects: Cell research; Mitosis; Physiological aspects; Special Issue on Quantitative Biology; Yeast fungi; United States

In favorable conditions, eukaryotic cells proceed irreversibly through the cell division cycle (G1-S-G2-M) in order to produce two daughter cells with the same number and identity of chromosomes of their progenitor. The integrity of this process is maintained by “checkpoints” that hold a cell at par...