Asymmetric synthesis of stereogenic-at-iridium(III) complexes through Pd-catalyzed kinetic resolution

• Published in: Nature communications Vol. 16; no. 1; pp. 1177 - 10
• Main Authors: Chu, Yun-Peng, Yue, Xue-Lin, Liu, De-Hai, Wang, Chuanyong, Ma, Jiajia
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 30.01.2025; Nature Publishing Group; Nature Portfolio
• Subjects: 639/638/403/933; 639/638/403/935; Asymmetric synthesis; Asymmetry; Catalysis; Chemical reactions; Chemical synthesis; Chirality; Coordination compounds; Coupling (molecular); Cross coupling; Humanities and Social Sciences; Iridium; Iridium compounds; Metal complexes; Metal ions; multidisciplinary; Optical activity; Organic chemistry; Palladium; Science; Science (multidisciplinary)

Metal-centered chirality has been recognized for over one century, and stereogenic-at-metal complexes where chirality is exclusively attributed to the metal center due to the specific coordination pattern of achiral ligands around the metal ion, has been broadly utilized in diverse areas of natural...