Efficacy and Safety Extrapolation Analyses for Atomoxetine in Young Children with Attention-Deficit/Hyperactivity Disorder

• Published in: Journal of child and adolescent psychopharmacology Vol. 25; no. 10; pp. 799 - 809
• Main Authors: Upadhyaya, Himanshu, Kratochvil, Christopher, Ghuman, Jaswinder, Camporeale, Angelo, Lipsius, Sarah, D'Souza, Deborah, Tanaka, Yoko
• Format: Journal Article
• Language: English
• Published: United States Mary Ann Liebert, Inc 01.12.2015
• Subjects: Adrenergic Uptake Inhibitors - adverse effects; Adrenergic Uptake Inhibitors - therapeutic use; Age Factors; Analysis; Atomoxetine Hydrochloride - adverse effects; Atomoxetine Hydrochloride - therapeutic use; Attention Deficit Disorder with Hyperactivity - drug therapy; Attention deficit hyperactivity disorder; Child; Child, Preschool; Children & youth; Double-Blind Method; Female; Humans; Male; Original; Randomized Controlled Trials as Topic; Safety

This extrapolation analysis qualitatively compared the efficacy and safety profile of atomoxetine from Lilly clinical trial data in 6-7-year-old patients with attention-deficit/hyperactivity disorder (ADHD) with that of published literature in 4-5-year-old patients with ADHD (two open-label [4-5-yea...