Direct Estimate of the Spontaneous Mutation Rate Uncovers the Effects of Drift and Recombination in the Chlamydomonas reinhardtii Plastid Genome

• Published in: Molecular biology and evolution Vol. 33; no. 3; pp. 800 - 808
• Main Authors: Ness, Rob W., Kraemer, Susanne A., Colegrave, Nick, Keightley, Peter D.
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.03.2016
• Subjects: Algae; Base Composition; Chlamydomonas reinhardtii; Chlamydomonas reinhardtii - genetics; Deoxyribonucleic acid; DNA; Estimating techniques; Eukaryotes; Gene regulation; Gene sequencing; Genetic Drift; Genetics, Population; Genome, Plastid; Genomes; Linkage disequilibrium; Mutation; Mutation Rate; Mutation rates; Photosynthesis; Plastids; Polymorphism, Genetic; Recombination; Recombination, Genetic; plastid genome; effective population size; mutation rate; recombination; chloroplast; Chlamydomonas reinhardtii

Plastids perform crucial cellular functions, including photosynthesis, across a wide variety of eukaryotes. Since endosymbiosis, plastids have maintained independent genomes that now display a wide diversity of gene content, genome structure, gene regulation mechanisms, and transmission modes. The e...