An inclusive study on cytokine gene expression in Parkinson's disease: Advanced analysis using Bayesian regression model

• Published in: Human immunology Vol. 84; no. 2; pp. 123 - 129
• Main Authors: Moradi, Shadi, Zamani, Alireza, Mazdeh, Mehrdokht, Ramezani, Mahdi, Komaki, Alireza, Talebi-Ghane, Elahe, Mahdi Eftekharian, Mohammad
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2023
• Subjects: Aged; Bayes Theorem; Chemokine; Cytokine; Cytokines - genetics; Female; Gene Expression; Humans; Inflammation; Interleukin-17 - genetics; Interleukin-2 - genetics; Interleukin-4 - genetics; Interleukin-6 - genetics; Neurodegenerative Diseases; Parkinson Disease - genetics; Parkinson's disease; Tumor Necrosis Factor-alpha - genetics; Chemokine; Inflammation; Parkinson's disease; Cytokine
• ISSN: 0198-8859; 1879-1166; 1879-1166
• DOI: 10.1016/j.humimm.2022.11.001

Parkinson's disease (PD) is the second most prevalent neurodegenerative disease throughout the globe whose specific pathophysiology is unknown. Researchers believe that inflammation and oxidative stress contribute to PD development. Also, alterations in cytokines production appear to have a key...