Maintenance tegafur-plus-uracil after adjuvant concurrent chemoradiotherapy may improve outcome for resected oral cavity squamous cell carcinoma with extranodal extension

• Published in: Frontiers in oncology Vol. 12; p. 866890
• Main Authors: Huang, Pei-Wei, Lin, Chien-Yu, Lee, Li-Yu, Hsieh, Chia-Hsun, Hsu, Cheng-Lung, Liau, Chi-Ting, Fan, Kang-Hsing, Huang, Shiang-Fu, Liao, Chun-Ta, Chang, Tung-Chieh, Wang, Hung-Ming
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 28.09.2022
• Subjects: extranodal extension; head and neck cancer; maintenance therapy; oligometastasis; Oncology; tegafur plus uracil; tegafur plus uracil; maintenance therapy; oligometastasis; head and neck cancer; extranodal extension

To evaluate whether tegafur-uracil maintenance (UFTm) following postoperation adjuvant cisplatin-based concurrent chemoradiotherapy (CCRT) may reduce distant metastasis in patients with resected oral cavity squamous cell carcinoma (OSCC) with pathologic extranodal extension (pENE+). A retrospective...