Aminosuberoyl hydroxamic acids (ASHAs): A potent new class of HDAC inhibitors
Exploring branched substrate-like HDAC inhibitors, mimicking the peptide substrate, lead to a series of aminosuberoyl hydroxamic acids (ASHAs) with remarkable HDAC inhibitory activity. Histone deacetylase (HDAC) inhibitors that target Class I and Class II HDACs are currently in advanced clinical tri...
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Published in | Bioorganic & medicinal chemistry letters Vol. 17; no. 14; pp. 3969 - 3971 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford
Elsevier Ltd
15.07.2007
Elsevier |
Subjects | |
Online Access | Get full text |
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